FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1490397100> ?p ?o ?g. }

• W1490397100 endingPage "1237" @default.
• W1490397100 startingPage "1227" @default.
• W1490397100 abstract "Object Damage to axons contributes to postinjury disabilities and is commonly observed following traumatic brain injury (TBI). Traumatic brain injury is an important environmental risk factor for the development of Alzheimer disease (AD). In the present feasibility study, the aim was to use intracerebral microdialysis catheters with a high molecular cutoff membrane (100 kD) to harvest interstitial total tau (T-tau) and amyloid beta 1–42 (Aβ42) proteins, which are important biomarkers for axonal injury and for AD, following moderate-to-severe TBI. Methods Eight patients (5 men and 3 women) were included in the study; 5 of the patients had a focal/mixed TBI and 3 had a diffuse axonal injury (DAI). Following the bedside analysis of the routinely measured energy metabolic markers (that is, glucose, lactate/pyruvate ratio, glycerol, and glutamate), the remaining dialysate was pooled and two 12-hour samples per day were used to analyze T-tau and Aβ42 by enzyme-linked immunosorbent assay from Day 1 up to 8 days postinjury. Results The results show high levels of interstitial T-tau and Aβ42 postinjury. Patients with a predominantly focal lesion had higher interstitial T-tau levels than in the DAI group from Days 1 to 3 postinjury (p < 0.05). In contrast, patients with DAI had consistently higher Aβ42 levels when compared with patients with focal injury. Conclusions These results suggest that monitoring of interstitial T-tau and Aβ42 by using microdialysis may be an important tool when evaluating the presence and role of axonal injury following TBI." @default.
• W1490397100 created "2016-06-24" @default.
• W1490397100 creator A5009788180 @default.
• W1490397100 creator A5062898791 @default.
• W1490397100 creator A5068394264 @default.
• W1490397100 creator A5075741298 @default.
• W1490397100 creator A5082050889 @default.
• W1490397100 creator A5091785793 @default.
• W1490397100 date "2009-06-01" @default.
• W1490397100 modified "2023-10-17" @default.
• W1490397100 title "Monitoring of brain interstitial total tau and beta amyloid proteins by microdialysis in patients with traumatic brain injury" @default.
• W1490397100 cites W1581789419 @default.
• W1490397100 cites W1879457624 @default.
• W1490397100 cites W1955491145 @default.
• W1490397100 cites W1965918817 @default.
• W1490397100 cites W1966278423 @default.
• W1490397100 cites W1967874285 @default.
• W1490397100 cites W1967993221 @default.
• W1490397100 cites W1968563974 @default.
• W1490397100 cites W1980574163 @default.
• W1490397100 cites W1985722784 @default.
• W1490397100 cites W1987733774 @default.
• W1490397100 cites W1989719980 @default.
• W1490397100 cites W1991492504 @default.
• W1490397100 cites W1994278260 @default.
• W1490397100 cites W1994365168 @default.
• W1490397100 cites W1998069455 @default.
• W1490397100 cites W1999082266 @default.
• W1490397100 cites W2009105636 @default.
• W1490397100 cites W2011949052 @default.
• W1490397100 cites W2013003446 @default.
• W1490397100 cites W2029934068 @default.
• W1490397100 cites W2031375851 @default.
• W1490397100 cites W2035564116 @default.
• W1490397100 cites W2035680108 @default.
• W1490397100 cites W2041802741 @default.
• W1490397100 cites W2054384828 @default.
• W1490397100 cites W2057766834 @default.
• W1490397100 cites W2065904280 @default.
• W1490397100 cites W2066376812 @default.
• W1490397100 cites W2070045579 @default.
• W1490397100 cites W2070093850 @default.
• W1490397100 cites W2070806188 @default.
• W1490397100 cites W2070887142 @default.
• W1490397100 cites W2073009405 @default.
• W1490397100 cites W2074451536 @default.
• W1490397100 cites W2075304472 @default.
• W1490397100 cites W2076782787 @default.
• W1490397100 cites W2078295190 @default.
• W1490397100 cites W2079036536 @default.
• W1490397100 cites W2081207317 @default.
• W1490397100 cites W2082556367 @default.
• W1490397100 cites W2084817972 @default.
• W1490397100 cites W2084904591 @default.
• W1490397100 cites W2085268501 @default.
• W1490397100 cites W2085851888 @default.
• W1490397100 cites W2086651792 @default.
• W1490397100 cites W2086701519 @default.
• W1490397100 cites W2087394638 @default.
• W1490397100 cites W2090496922 @default.
• W1490397100 cites W2091184929 @default.
• W1490397100 cites W2099570666 @default.
• W1490397100 cites W2103982815 @default.
• W1490397100 cites W2116560770 @default.
• W1490397100 cites W2124135429 @default.
• W1490397100 cites W2133019124 @default.
• W1490397100 cites W2136321913 @default.
• W1490397100 cites W2143224908 @default.
• W1490397100 cites W2154813265 @default.
• W1490397100 cites W2155784539 @default.
• W1490397100 cites W2164474430 @default.
• W1490397100 cites W2267414220 @default.
• W1490397100 cites W2740036250 @default.
• W1490397100 cites W36773920 @default.
• W1490397100 cites W4211156109 @default.
• W1490397100 cites W4251671944 @default.
• W1490397100 cites W4362116953 @default.
• W1490397100 doi "https://doi.org/10.3171/2008.9.jns08584" @default.
• W1490397100 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19216653" @default.
• W1490397100 hasPublicationYear "2009" @default.
• W1490397100 type Work @default.
• W1490397100 sameAs 1490397100 @default.
• W1490397100 citedByCount "118" @default.
• W1490397100 countsByYear W14903971002012 @default.
• W1490397100 countsByYear W14903971002013 @default.
• W1490397100 countsByYear W14903971002014 @default.
• W1490397100 countsByYear W14903971002015 @default.
• W1490397100 countsByYear W14903971002016 @default.
• W1490397100 countsByYear W14903971002017 @default.
• W1490397100 countsByYear W14903971002018 @default.
• W1490397100 countsByYear W14903971002019 @default.
• W1490397100 countsByYear W14903971002020 @default.
• W1490397100 countsByYear W14903971002021 @default.
• W1490397100 countsByYear W14903971002022 @default.
• W1490397100 countsByYear W14903971002023 @default.
• W1490397100 crossrefType "journal-article" @default.
• W1490397100 hasAuthorship W1490397100A5009788180 @default.
• W1490397100 hasAuthorship W1490397100A5062898791 @default.

• next