FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1490448519> ?p ?o ?g. }

• W1490448519 endingPage "411" @default.
• W1490448519 startingPage "400" @default.
• W1490448519 abstract "OBJECT High-grade malignant spinal cord compression is commonly managed with a combination of surgery aimed at removing the epidural tumor, followed by spinal stereotactic radiosurgery (SSRS) aimed at local tumor control. The authors here introduce the use of spinal laser interstitial thermotherapy (SLITT) as an alternative to surgery prior to SSRS. METHODS Patients with a high degree of epidural malignant compression due to radioresistant tumors were selected for study. Visual analog scale (VAS) scores for pain and quality of life were obtained before and within 30 and 60 days after treatment. A laser probe was percutaneously placed in the epidural space. Real-time thermal MRI was used to monitor tissue damage in the region of interest. All patients received postoperative SSRS. The maximum thickness of the epidural tumor was measured, and the degree of epidural spinal cord compression (ESCC) was scored in pre- and postprocedure MRI. RESULTS In the 11 patients eligible for study, the mean VAS score for pain decreased from 6.18 in the preoperative period to 4.27 within 30 days and 2.8 within 60 days after the procedure. A similar VAS interrogating the percentage of quality of life demonstrated improvement from 60% preoperatively to 70% within both 30 and 60 days after treatment. Imaging follow-up 2 months after the procedure demonstrated a significant reduction in the mean thickness of the epidural tumor from 8.82 mm (95% CI 7.38–10.25) before treatment to 6.36 mm (95% CI 4.65–8.07) after SLITT and SSRS (p = 0.0001). The median preoperative ESCC Grade 2 was scored as 4, which was significantly higher than the score of 2 for Grade 1b (p = 0.04) on imaging follow-up 2 months after the procedure. CONCLUTIONS The authors present the first report on an innovative minimally invasive alternative to surgery in the management of spinal metastasis. In their early experience, SLITT has provided local control with low morbidity and improvement in both pain and the quality of life of patients." @default.
• W1490448519 created "2016-06-24" @default.
• W1490448519 creator A5001637862 @default.
• W1490448519 creator A5008540539 @default.
• W1490448519 creator A5012677271 @default.
• W1490448519 creator A5017578103 @default.
• W1490448519 creator A5020606620 @default.
• W1490448519 creator A5051760579 @default.
• W1490448519 creator A5054514877 @default.
• W1490448519 creator A5061333234 @default.
• W1490448519 creator A5061781272 @default.
• W1490448519 creator A5066408894 @default.
• W1490448519 creator A5067520533 @default.
• W1490448519 creator A5071029052 @default.
• W1490448519 creator A5071575774 @default.
• W1490448519 date "2015-10-01" @default.
• W1490448519 modified "2023-10-17" @default.
• W1490448519 title "Utilization of laser interstitial thermotherapy guided by real-time thermal MRI as an alternative to separation surgery in the management of spinal metastasis" @default.
• W1490448519 cites W1499110203 @default.
• W1490448519 cites W1583826198 @default.
• W1490448519 cites W1946825180 @default.
• W1490448519 cites W1965531668 @default.
• W1490448519 cites W1966488552 @default.
• W1490448519 cites W1966820923 @default.
• W1490448519 cites W1967790021 @default.
• W1490448519 cites W1969293642 @default.
• W1490448519 cites W1970088618 @default.
• W1490448519 cites W1976901971 @default.
• W1490448519 cites W1979893421 @default.
• W1490448519 cites W1984547579 @default.
• W1490448519 cites W1986920424 @default.
• W1490448519 cites W2002039079 @default.
• W1490448519 cites W2008090724 @default.
• W1490448519 cites W2009202244 @default.
• W1490448519 cites W2023944665 @default.
• W1490448519 cites W2027015805 @default.
• W1490448519 cites W2029958280 @default.
• W1490448519 cites W2040679579 @default.
• W1490448519 cites W2045710628 @default.
• W1490448519 cites W2052656085 @default.
• W1490448519 cites W2070204552 @default.
• W1490448519 cites W2077080208 @default.
• W1490448519 cites W2086608538 @default.
• W1490448519 cites W2086645764 @default.
• W1490448519 cites W2096523829 @default.
• W1490448519 cites W2100625706 @default.
• W1490448519 cites W2104302044 @default.
• W1490448519 cites W2110069491 @default.
• W1490448519 cites W2129174433 @default.
• W1490448519 cites W2129940374 @default.
• W1490448519 cites W2143853878 @default.
• W1490448519 cites W2161933541 @default.
• W1490448519 cites W2252887828 @default.
• W1490448519 cites W2318203456 @default.
• W1490448519 cites W2473786944 @default.
• W1490448519 cites W2792716634 @default.
• W1490448519 cites W6687156 @default.
• W1490448519 doi "https://doi.org/10.3171/2015.2.spine141185" @default.
• W1490448519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26140398" @default.
• W1490448519 hasPublicationYear "2015" @default.
• W1490448519 type Work @default.
• W1490448519 sameAs 1490448519 @default.
• W1490448519 citedByCount "73" @default.
• W1490448519 countsByYear W14904485192016 @default.
• W1490448519 countsByYear W14904485192017 @default.
• W1490448519 countsByYear W14904485192018 @default.
• W1490448519 countsByYear W14904485192019 @default.
• W1490448519 countsByYear W14904485192020 @default.
• W1490448519 countsByYear W14904485192021 @default.
• W1490448519 countsByYear W14904485192022 @default.
• W1490448519 countsByYear W14904485192023 @default.
• W1490448519 crossrefType "journal-article" @default.
• W1490448519 hasAuthorship W1490448519A5001637862 @default.
• W1490448519 hasAuthorship W1490448519A5008540539 @default.
• W1490448519 hasAuthorship W1490448519A5012677271 @default.
• W1490448519 hasAuthorship W1490448519A5017578103 @default.
• W1490448519 hasAuthorship W1490448519A5020606620 @default.
• W1490448519 hasAuthorship W1490448519A5051760579 @default.
• W1490448519 hasAuthorship W1490448519A5054514877 @default.
• W1490448519 hasAuthorship W1490448519A5061333234 @default.
• W1490448519 hasAuthorship W1490448519A5061781272 @default.
• W1490448519 hasAuthorship W1490448519A5066408894 @default.
• W1490448519 hasAuthorship W1490448519A5067520533 @default.
• W1490448519 hasAuthorship W1490448519A5071029052 @default.
• W1490448519 hasAuthorship W1490448519A5071575774 @default.
• W1490448519 hasBestOaLocation W14904485191 @default.
• W1490448519 hasConcept C118552586 @default.
• W1490448519 hasConcept C126838900 @default.
• W1490448519 hasConcept C141071460 @default.
• W1490448519 hasConcept C14184104 @default.
• W1490448519 hasConcept C143409427 @default.
• W1490448519 hasConcept C159110408 @default.
• W1490448519 hasConcept C2777657843 @default.
• W1490448519 hasConcept C2778231337 @default.
• W1490448519 hasConcept C2779951463 @default.
• W1490448519 hasConcept C2780387249 @default.
• W1490448519 hasConcept C2780775167 @default.
• W1490448519 hasConcept C2989005 @default.

• next