FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1490760366> ?p ?o ?g. }

• W1490760366 endingPage "38" @default.
• W1490760366 startingPage "25" @default.
• W1490760366 abstract "To further characterize the neuropathology of the heterogeneous molecular disorder frontotemporal lobar degeneration (FTLD) with transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) proteinopathy (FTLD-TDP).We quantified the neuronal cytoplasmic inclusions, glial inclusions, neuronal intranuclear inclusions, dystrophic neurites, surviving neurones, abnormally enlarged neurones, and vacuoles in regions of the frontal and temporal lobe using a phosphorylation-independent TDP-43 antibody in 32 cases of FTLD-TDP comprising sporadic and familial cases, with associated pathology such as hippocampal sclerosis (HS) or Alzheimer's disease (AD), and four neuropathological subtypes using TDP-43 immunohistochemistry. Analysis of variance (anova) was used to compare differences between the various groups of cases.These data from FTLD-TDP cases demonstrate quantitative differences in pathological features between: (i) regions of the frontal and temporal lobe; (ii) upper and lower cortex; (iii) sporadic and progranulin (GRN) mutation cases; (iv) cases with and without AD or HS; and (v) between assigned subtypes.The data confirm that the dentate gyrus is a major site of neuropathology in FTLD-TDP and that most laminae of the cerebral cortex are affected. GRN mutation cases are quantitatively different from sporadic cases, while cases with associated HS and AD have increased densities of dystrophic neurites and abnormally enlarged neurones respectively. There is little correlation between the subjective assessment of subtypes and the more objective quantitative data." @default.
• W1490760366 created "2016-06-24" @default.
• W1490760366 creator A5040571169 @default.
• W1490760366 creator A5072010327 @default.
• W1490760366 creator A5082220804 @default.
• W1490760366 date "2012-01-06" @default.
• W1490760366 modified "2023-10-06" @default.
• W1490760366 title "A quantitative study of the neuropathology of 32 sporadic and familial cases of frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP)" @default.
• W1490760366 cites W181718899 @default.
• W1490760366 cites W1964347491 @default.
• W1490760366 cites W1966280878 @default.
• W1490760366 cites W1967674497 @default.
• W1490760366 cites W1971895317 @default.
• W1490760366 cites W1978702147 @default.
• W1490760366 cites W1981625094 @default.
• W1490760366 cites W1983431610 @default.
• W1490760366 cites W1983768810 @default.
• W1490760366 cites W1989763172 @default.
• W1490760366 cites W1989872027 @default.
• W1490760366 cites W1990580907 @default.
• W1490760366 cites W1999250322 @default.
• W1490760366 cites W2004395649 @default.
• W1490760366 cites W2005731595 @default.
• W1490760366 cites W2008616648 @default.
• W1490760366 cites W2014529472 @default.
• W1490760366 cites W2016514980 @default.
• W1490760366 cites W2018505720 @default.
• W1490760366 cites W2020280724 @default.
• W1490760366 cites W2027374588 @default.
• W1490760366 cites W2027460468 @default.
• W1490760366 cites W2032523424 @default.
• W1490760366 cites W2038879822 @default.
• W1490760366 cites W2041451000 @default.
• W1490760366 cites W2046534863 @default.
• W1490760366 cites W2051349033 @default.
• W1490760366 cites W2053216332 @default.
• W1490760366 cites W2057560661 @default.
• W1490760366 cites W2063406161 @default.
• W1490760366 cites W2074107194 @default.
• W1490760366 cites W2079596501 @default.
• W1490760366 cites W2086368392 @default.
• W1490760366 cites W2091173932 @default.
• W1490760366 cites W2092646825 @default.
• W1490760366 cites W2093650784 @default.
• W1490760366 cites W2099522162 @default.
• W1490760366 cites W2104658204 @default.
• W1490760366 cites W2125863122 @default.
• W1490760366 cites W2126512957 @default.
• W1490760366 cites W2129594328 @default.
• W1490760366 cites W2134408741 @default.
• W1490760366 cites W2136057227 @default.
• W1490760366 cites W2146913804 @default.
• W1490760366 cites W2163955717 @default.
• W1490760366 cites W2165666114 @default.
• W1490760366 cites W2168929061 @default.
• W1490760366 cites W2322852998 @default.
• W1490760366 doi "https://doi.org/10.1111/j.1365-2990.2011.01188.x" @default.
• W1490760366 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3206199" @default.
• W1490760366 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21696412" @default.
• W1490760366 hasPublicationYear "2012" @default.
• W1490760366 type Work @default.
• W1490760366 sameAs 1490760366 @default.
• W1490760366 citedByCount "16" @default.
• W1490760366 countsByYear W14907603662013 @default.
• W1490760366 countsByYear W14907603662014 @default.
• W1490760366 countsByYear W14907603662016 @default.
• W1490760366 countsByYear W14907603662019 @default.
• W1490760366 countsByYear W14907603662020 @default.
• W1490760366 countsByYear W14907603662021 @default.
• W1490760366 countsByYear W14907603662022 @default.
• W1490760366 crossrefType "journal-article" @default.
• W1490760366 hasAuthorship W1490760366A5040571169 @default.
• W1490760366 hasAuthorship W1490760366A5072010327 @default.
• W1490760366 hasAuthorship W1490760366A5082220804 @default.
• W1490760366 hasBestOaLocation W14907603662 @default.
• W1490760366 hasConcept C142724271 @default.
• W1490760366 hasConcept C169760540 @default.
• W1490760366 hasConcept C207886595 @default.
• W1490760366 hasConcept C2776939681 @default.
• W1490760366 hasConcept C2777127467 @default.
• W1490760366 hasConcept C2777597344 @default.
• W1490760366 hasConcept C2778186239 @default.
• W1490760366 hasConcept C2778641062 @default.
• W1490760366 hasConcept C2779134260 @default.
• W1490760366 hasConcept C2779483572 @default.
• W1490760366 hasConcept C2780130745 @default.
• W1490760366 hasConcept C2781099131 @default.
• W1490760366 hasConcept C71924100 @default.
• W1490760366 hasConcept C86803240 @default.
• W1490760366 hasConceptScore W1490760366C142724271 @default.
• W1490760366 hasConceptScore W1490760366C169760540 @default.
• W1490760366 hasConceptScore W1490760366C207886595 @default.
• W1490760366 hasConceptScore W1490760366C2776939681 @default.
• W1490760366 hasConceptScore W1490760366C2777127467 @default.
• W1490760366 hasConceptScore W1490760366C2777597344 @default.
• W1490760366 hasConceptScore W1490760366C2778186239 @default.
• W1490760366 hasConceptScore W1490760366C2778641062 @default.
• W1490760366 hasConceptScore W1490760366C2779134260 @default.

• next