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- W1491365291 abstract "Abstract : To examine the mechanisms by which melanopeptides and hypertonic saline activate pressor mechanisms during hemorrhagic shock. Approach: Hemorrhagic shock is induced in rats by the controlled withdrawal of specific blood volumes, graded by body weight. Mean arterial pressure (MAP) and heart rate (HR) serve as indices of cardiovascular flinction, and ultimately as indicators of hemorrhage-induced shock. In this model of hemorrhagic shock, the melanopeptide, y-MSH, is administered peripherally or centrally, post-hemorrhage, to determine the therapeutic potential of the compound in treating hemorrhagic shock. The ability of y-MSH and hypertonic saline to increase survivability under the condition of hemorrhagic shock is being evaluated." @default.
- W1491365291 created "2016-06-24" @default.
- W1491365291 creator A5055756006 @default.
- W1491365291 date "2003-02-28" @default.
- W1491365291 modified "2023-10-17" @default.
- W1491365291 title "Receptors, Afferent Signaling and Central Integration in Compensated and Uncompensated Hemorrhagic Shock" @default.
- W1491365291 doi "https://doi.org/10.21236/ada411512" @default.
- W1491365291 hasPublicationYear "2003" @default.
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