Matches in SemOpenAlex for { <https://semopenalex.org/work/W1491603175> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W1491603175 endingPage "59" @default.
- W1491603175 startingPage "55" @default.
- W1491603175 abstract "Abstract Spinach leaf ribulose 1,5-diphosphate carboxylase is reversibly inhibited by cyanide at low concentration; 10-5 m and 10-4 m cyanide inhibit the carboxylation reaction 51% and 91%, respectively. Inhibition by cyanide (Ki = 1.6 x 10-5 m) is uncompetitive (anticompetitive) with respect to ribulose 1,5-diphosphate (ribulose-1,5-di-P) and is of mixed character with respect to Mg2+ and HCO3-. This and other kinetic evidence suggest that cyanide combines readily with enzyme-ribulose-1,5-di-P complex, but not with enzyme. The inference that enzyme-ribulose-1,5-di-P complex reacts with cyanide to form an inactive ternary complex is supported by binding studies with the use of the gel filtration technique. Ribulose-1,5-di-P uniformly labeled with 14C is tightly bound to the carboxylase (1.04 moles of ribulose-1,5-di-P per mole of enzyme) only in the presence of cyanide and 14C-cyanide is bound to the carboxylase (1.06 moles of cyanide per mole of enzyme) only in the presence of ribulose-1,5-di-P. The presence of Mg2+ is without effect on 14C-ribulose-1,5-di-P binding in the presence of cyanide or on 14C-cyanide binding in the presence of ribulose-1,5-di-P under the conditions used. A ternary complex of ribulose-1,5-di-P carboxylase, ribulose-1,5-di-P, and cyanide in a mole ratio of 1:1:1 is indicated. Attempts to demonstrate Schiff base formation between the carboxylase and ribulose-1,5-di-P under a wide variety of conditions were unsuccessful." @default.
- W1491603175 created "2016-06-24" @default.
- W1491603175 creator A5012475457 @default.
- W1491603175 creator A5021750317 @default.
- W1491603175 date "1969-01-01" @default.
- W1491603175 modified "2023-10-16" @default.
- W1491603175 title "Inhibition of Ribulose Diphosphate Carboxylase by Cyanide" @default.
- W1491603175 cites W1517105356 @default.
- W1491603175 cites W1524711591 @default.
- W1491603175 cites W1580784802 @default.
- W1491603175 cites W1581940947 @default.
- W1491603175 cites W1606884205 @default.
- W1491603175 cites W2000720185 @default.
- W1491603175 cites W2004760794 @default.
- W1491603175 cites W2017561470 @default.
- W1491603175 cites W2023098438 @default.
- W1491603175 cites W2069210385 @default.
- W1491603175 cites W2079357166 @default.
- W1491603175 cites W2089188790 @default.
- W1491603175 cites W2410727875 @default.
- W1491603175 cites W3118517130 @default.
- W1491603175 doi "https://doi.org/10.1016/s0021-9258(19)78190-3" @default.
- W1491603175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5773288" @default.
- W1491603175 hasPublicationYear "1969" @default.
- W1491603175 type Work @default.
- W1491603175 sameAs 1491603175 @default.
- W1491603175 citedByCount "74" @default.
- W1491603175 countsByYear W14916031752012 @default.
- W1491603175 countsByYear W14916031752014 @default.
- W1491603175 countsByYear W14916031752015 @default.
- W1491603175 countsByYear W14916031752016 @default.
- W1491603175 countsByYear W14916031752017 @default.
- W1491603175 countsByYear W14916031752018 @default.
- W1491603175 countsByYear W14916031752019 @default.
- W1491603175 countsByYear W14916031752022 @default.
- W1491603175 crossrefType "journal-article" @default.
- W1491603175 hasAuthorship W1491603175A5012475457 @default.
- W1491603175 hasAuthorship W1491603175A5021750317 @default.
- W1491603175 hasBestOaLocation W14916031751 @default.
- W1491603175 hasConcept C140137476 @default.
- W1491603175 hasConcept C178790620 @default.
- W1491603175 hasConcept C181199279 @default.
- W1491603175 hasConcept C185592680 @default.
- W1491603175 hasConcept C2778455166 @default.
- W1491603175 hasConcept C2779966244 @default.
- W1491603175 hasConcept C55493867 @default.
- W1491603175 hasConceptScore W1491603175C140137476 @default.
- W1491603175 hasConceptScore W1491603175C178790620 @default.
- W1491603175 hasConceptScore W1491603175C181199279 @default.
- W1491603175 hasConceptScore W1491603175C185592680 @default.
- W1491603175 hasConceptScore W1491603175C2778455166 @default.
- W1491603175 hasConceptScore W1491603175C2779966244 @default.
- W1491603175 hasConceptScore W1491603175C55493867 @default.
- W1491603175 hasIssue "1" @default.
- W1491603175 hasLocation W14916031751 @default.
- W1491603175 hasOpenAccess W1491603175 @default.
- W1491603175 hasPrimaryLocation W14916031751 @default.
- W1491603175 hasRelatedWork W1422277532 @default.
- W1491603175 hasRelatedWork W1521287924 @default.
- W1491603175 hasRelatedWork W1535436060 @default.
- W1491603175 hasRelatedWork W1909464692 @default.
- W1491603175 hasRelatedWork W1977079987 @default.
- W1491603175 hasRelatedWork W2027858047 @default.
- W1491603175 hasRelatedWork W2037052967 @default.
- W1491603175 hasRelatedWork W2092398754 @default.
- W1491603175 hasRelatedWork W2171787368 @default.
- W1491603175 hasRelatedWork W2939404324 @default.
- W1491603175 hasVolume "244" @default.
- W1491603175 isParatext "false" @default.
- W1491603175 isRetracted "false" @default.
- W1491603175 magId "1491603175" @default.
- W1491603175 workType "article" @default.