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- W1492103659 abstract "This is a case report of a rare tumor of the testis, a large-cell calcifying Sertoli tumor (LCCSCT) in a 25 year old man; it was not associated with a genetic syndrome. Sertoli cell tumors are only found in less than 1% of testicular tumors, and LCCSCT is a variant with specific microscopic and clinical characteristics: a younger age group, and accompanied by gynecomastia and isosexual pseudoprecocity. The ultrastructure and immunophenotype are useful to indicate its Sertoli cell origin. The tumor can be associated with Carney’s complex with myxomas in heart, skin, soft tissues and breast, centrofacial maculas, blue nevi, pigmented adrenocortical hyperplasia, somatotrophic pituitary adenomas, psamomatous melanotic schwannoma, and other rarer findings. It is important in any patient with LCCSCT to look for the other components of Carney’s complex in order to prevent cardiac and embolic complications. Less frequently LCCSCT is associated with the Peutz-Jeghers syndrome. Most cases with LCCSCT are benign, although malignant cases have been described, with extratesticular extension, necrosis and atypical cytology. The treatment depends on whether or not it as associated with a genetic syndrome." @default.
- W1492103659 created "2016-06-24" @default.
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- W1492103659 date "2005-01-01" @default.
- W1492103659 modified "2023-09-27" @default.
- W1492103659 title "Tumor calcificante de células grandes de Sertoli" @default.
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