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- W1492148812 abstract "The skin and tear film contain complex mixtures of lipids that act individually or synergistically with proteins and peptides to provide strong antimicrobial barriers at the cutaneous and ocular surfaces. These lipids have antimicrobial activity when isolated from these tissues and tested against Gram-positive bacteria, Gram-negative bacteria, and yeasts. The spectrum of antimicrobial activity of lipids is currently under investigation by a variety of research groups for a variety of cutaneous pathogens. The site of lipid antimicrobial activity appears to be the microbial plasma membrane but this needs to be confirmed. Further investigation will likely identify promising lipids with strong antimicrobial activity, anti-inflammatory properties, and low toxicities for epithelial and mucosal tissues that may serve as therapeutics to treat a wide variety of cutaneous and ocular infections and inflammatory disorders." @default.
- W1492148812 created "2016-06-24" @default.
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- W1492148812 creator A5089790985 @default.
- W1492148812 date "2010-12-14" @default.
- W1492148812 modified "2023-09-26" @default.
- W1492148812 title "Antimicrobial Lipids of the Skin and Tear Film" @default.
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