Matches in SemOpenAlex for { <https://semopenalex.org/work/W1492181842> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1492181842 endingPage "672" @default.
- W1492181842 startingPage "667" @default.
- W1492181842 abstract "Scutellaria baicalensis Georgi (Labiatae) has been used in the treatment of inflammatory diseases. Drug processing (Poje) is the process of treating crude drugs by several methods before use. The aim of this study was to determine the effect of processed Scutellaria baicalensis on experimental ulcerative colitis induced by dextran sulfate sodium (DSS). The types of processed Scutellaria baicalensis used in this study were parched Scutellaria baicalensis (PS) and rice wine-baked Scutellaria baicalensis (RWBS). Experimental colitis was induced in mice using a daily treatment of 5% DSS in the drinking water for 7 days. The water extracts of processed Scutellaria baicalensis (1 g/kg) were administered orally once a day for 7 days. The mice were divided in four groups: i) water plus DSS group, ii) crude Scutellaria baicalensis (CS) plus DSS group, iii) PS plus DSS group, and iv) RWBS plus DSS group. RWBS ameliorated all of the inflammatory symptoms, such as body weight loss, rectal bleeding and histological damage, compared to CS. Furthermore, RWBS significantly reduced the mucosal myeloperoxidase activity, and TNF-α (tumor necrosis factor-α), COX-2 (cyclooxygenase-2), NF-κB (nuclear factor-kappa B) and chymase expression more than CS. But these effects were not shown in the PS plus DSS group. Efficacy of Scutellaria baicalensis was increased after rice wine baking, but not after parching. The findings in this study suggest that RWBS may be a useful therapeutic agent for ulcerative colitis." @default.
- W1492181842 created "2016-06-24" @default.
- W1492181842 creator A5000703027 @default.
- W1492181842 creator A5001973760 @default.
- W1492181842 creator A5005630627 @default.
- W1492181842 creator A5011637777 @default.
- W1492181842 creator A5015538936 @default.
- W1492181842 creator A5032408859 @default.
- W1492181842 creator A5039325507 @default.
- W1492181842 creator A5044391362 @default.
- W1492181842 creator A5047504790 @default.
- W1492181842 creator A5048511516 @default.
- W1492181842 creator A5054998515 @default.
- W1492181842 creator A5058177669 @default.
- W1492181842 creator A5061178178 @default.
- W1492181842 date "2005-10-01" @default.
- W1492181842 modified "2023-09-26" @default.
- W1492181842 title "Effect of processed Scutellaria baicalensis on dextran sulfate sodium-induced colitis in mice" @default.
- W1492181842 doi "https://doi.org/10.3892/ijmm.16.4.667" @default.
- W1492181842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16142402" @default.
- W1492181842 hasPublicationYear "2005" @default.
- W1492181842 type Work @default.
- W1492181842 sameAs 1492181842 @default.
- W1492181842 citedByCount "11" @default.
- W1492181842 countsByYear W14921818422012 @default.
- W1492181842 countsByYear W14921818422013 @default.
- W1492181842 countsByYear W14921818422014 @default.
- W1492181842 countsByYear W14921818422015 @default.
- W1492181842 countsByYear W14921818422017 @default.
- W1492181842 countsByYear W14921818422019 @default.
- W1492181842 countsByYear W14921818422020 @default.
- W1492181842 countsByYear W14921818422021 @default.
- W1492181842 countsByYear W14921818422023 @default.
- W1492181842 crossrefType "journal-article" @default.
- W1492181842 hasAuthorship W1492181842A5000703027 @default.
- W1492181842 hasAuthorship W1492181842A5001973760 @default.
- W1492181842 hasAuthorship W1492181842A5005630627 @default.
- W1492181842 hasAuthorship W1492181842A5011637777 @default.
- W1492181842 hasAuthorship W1492181842A5015538936 @default.
- W1492181842 hasAuthorship W1492181842A5032408859 @default.
- W1492181842 hasAuthorship W1492181842A5039325507 @default.
- W1492181842 hasAuthorship W1492181842A5044391362 @default.
- W1492181842 hasAuthorship W1492181842A5047504790 @default.
- W1492181842 hasAuthorship W1492181842A5048511516 @default.
- W1492181842 hasAuthorship W1492181842A5054998515 @default.
- W1492181842 hasAuthorship W1492181842A5058177669 @default.
- W1492181842 hasAuthorship W1492181842A5061178178 @default.
- W1492181842 hasConcept C126322002 @default.
- W1492181842 hasConcept C142724271 @default.
- W1492181842 hasConcept C185592680 @default.
- W1492181842 hasConcept C188947578 @default.
- W1492181842 hasConcept C204787440 @default.
- W1492181842 hasConcept C2775862500 @default.
- W1492181842 hasConcept C2778153525 @default.
- W1492181842 hasConcept C2779134260 @default.
- W1492181842 hasConcept C2780479503 @default.
- W1492181842 hasConcept C556039675 @default.
- W1492181842 hasConcept C71924100 @default.
- W1492181842 hasConcept C90924648 @default.
- W1492181842 hasConcept C98274493 @default.
- W1492181842 hasConceptScore W1492181842C126322002 @default.
- W1492181842 hasConceptScore W1492181842C142724271 @default.
- W1492181842 hasConceptScore W1492181842C185592680 @default.
- W1492181842 hasConceptScore W1492181842C188947578 @default.
- W1492181842 hasConceptScore W1492181842C204787440 @default.
- W1492181842 hasConceptScore W1492181842C2775862500 @default.
- W1492181842 hasConceptScore W1492181842C2778153525 @default.
- W1492181842 hasConceptScore W1492181842C2779134260 @default.
- W1492181842 hasConceptScore W1492181842C2780479503 @default.
- W1492181842 hasConceptScore W1492181842C556039675 @default.
- W1492181842 hasConceptScore W1492181842C71924100 @default.
- W1492181842 hasConceptScore W1492181842C90924648 @default.
- W1492181842 hasConceptScore W1492181842C98274493 @default.
- W1492181842 hasIssue "4" @default.
- W1492181842 hasLocation W14921818421 @default.
- W1492181842 hasLocation W14921818422 @default.
- W1492181842 hasOpenAccess W1492181842 @default.
- W1492181842 hasPrimaryLocation W14921818421 @default.
- W1492181842 hasRelatedWork W2025048290 @default.
- W1492181842 hasRelatedWork W2086156447 @default.
- W1492181842 hasRelatedWork W2154193834 @default.
- W1492181842 hasRelatedWork W2375240245 @default.
- W1492181842 hasRelatedWork W2464962541 @default.
- W1492181842 hasRelatedWork W2475104063 @default.
- W1492181842 hasRelatedWork W2748952813 @default.
- W1492181842 hasRelatedWork W2896381073 @default.
- W1492181842 hasRelatedWork W2899084033 @default.
- W1492181842 hasRelatedWork W3191366563 @default.
- W1492181842 hasVolume "16" @default.
- W1492181842 isParatext "false" @default.
- W1492181842 isRetracted "false" @default.
- W1492181842 magId "1492181842" @default.
- W1492181842 workType "article" @default.