Matches in SemOpenAlex for { <https://semopenalex.org/work/W149250840> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W149250840 endingPage "4" @default.
- W149250840 startingPage "310" @default.
- W149250840 abstract "Tetracyclines, particularly doxycycline, have adverse effects on granulocyte function in vitro. We have examined the effects of doxycycline on membrane receptors for IgG (Fc gamma-R) and C3b (C3b-R) on granulocytes and lymphocytes, as well as on the sheep erythrocyte receptor (E-R) on T lymphocytes. Acne patients given doxycycline orally had a lower percentage of Fc gamma-R positive granulocytes (57%) than before treatment (80%) or compared to healthy controls (81%). Following in vitro doxycycline incubation, normal granulocytes showed decreased levels of Fc gamma-R positive cells. This effect was counteracted by the addition of magnesium during incubation. The deleterious effect of doxycycline on granulocyte functions may be due to decreased levels of Fc gamma-R bearing granulocytes. Doxycycline in vivo or in vitro had no significant effect on the proportion of C3b-R bearing granulocytes or lymphocytes or the T lymphocyte percentage. After in vitro irradiation with light at 340-380 nm, however, both granulocytes and lymphocytes preincubated with doxycycline showed up to 50% decrease in Fc gamma-R bearing cells, while control cells without doxycycline were unaffected." @default.
- W149250840 created "2016-06-24" @default.
- W149250840 creator A5033042720 @default.
- W149250840 creator A5049256903 @default.
- W149250840 creator A5049790842 @default.
- W149250840 creator A5053091389 @default.
- W149250840 creator A5065113213 @default.
- W149250840 date "1985-11-01" @default.
- W149250840 modified "2023-09-23" @default.
- W149250840 title "In vivo and in vitro effects of doxycycline on leucocyte membrane receptors." @default.
- W149250840 cites W1556955543 @default.
- W149250840 cites W1974580479 @default.
- W149250840 cites W1981177318 @default.
- W149250840 cites W2007293778 @default.
- W149250840 cites W2023344389 @default.
- W149250840 cites W2031130184 @default.
- W149250840 cites W2058784090 @default.
- W149250840 cites W2091617175 @default.
- W149250840 cites W2102633124 @default.
- W149250840 cites W2118363232 @default.
- W149250840 cites W2380354478 @default.
- W149250840 cites W2419264281 @default.
- W149250840 cites W2428240508 @default.
- W149250840 cites W2433512011 @default.
- W149250840 cites W24778301 @default.
- W149250840 cites W329904465 @default.
- W149250840 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1577442" @default.
- W149250840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2935335" @default.
- W149250840 hasPublicationYear "1985" @default.
- W149250840 type Work @default.
- W149250840 sameAs 149250840 @default.
- W149250840 citedByCount "2" @default.
- W149250840 crossrefType "journal-article" @default.
- W149250840 hasAuthorship W149250840A5033042720 @default.
- W149250840 hasAuthorship W149250840A5049256903 @default.
- W149250840 hasAuthorship W149250840A5049790842 @default.
- W149250840 hasAuthorship W149250840A5053091389 @default.
- W149250840 hasAuthorship W149250840A5065113213 @default.
- W149250840 hasConcept C150903083 @default.
- W149250840 hasConcept C170493617 @default.
- W149250840 hasConcept C202751555 @default.
- W149250840 hasConcept C203014093 @default.
- W149250840 hasConcept C207001950 @default.
- W149250840 hasConcept C25642318 @default.
- W149250840 hasConcept C2777179404 @default.
- W149250840 hasConcept C2777761686 @default.
- W149250840 hasConcept C2777983669 @default.
- W149250840 hasConcept C501593827 @default.
- W149250840 hasConcept C55493867 @default.
- W149250840 hasConcept C86803240 @default.
- W149250840 hasConcept C89423630 @default.
- W149250840 hasConceptScore W149250840C150903083 @default.
- W149250840 hasConceptScore W149250840C170493617 @default.
- W149250840 hasConceptScore W149250840C202751555 @default.
- W149250840 hasConceptScore W149250840C203014093 @default.
- W149250840 hasConceptScore W149250840C207001950 @default.
- W149250840 hasConceptScore W149250840C25642318 @default.
- W149250840 hasConceptScore W149250840C2777179404 @default.
- W149250840 hasConceptScore W149250840C2777761686 @default.
- W149250840 hasConceptScore W149250840C2777983669 @default.
- W149250840 hasConceptScore W149250840C501593827 @default.
- W149250840 hasConceptScore W149250840C55493867 @default.
- W149250840 hasConceptScore W149250840C86803240 @default.
- W149250840 hasConceptScore W149250840C89423630 @default.
- W149250840 hasIssue "2" @default.
- W149250840 hasLocation W1492508401 @default.
- W149250840 hasOpenAccess W149250840 @default.
- W149250840 hasPrimaryLocation W1492508401 @default.
- W149250840 hasRelatedWork W2003310742 @default.
- W149250840 hasRelatedWork W2033951810 @default.
- W149250840 hasRelatedWork W2062291765 @default.
- W149250840 hasRelatedWork W2081783723 @default.
- W149250840 hasRelatedWork W2095350979 @default.
- W149250840 hasRelatedWork W2127819760 @default.
- W149250840 hasRelatedWork W2162079148 @default.
- W149250840 hasRelatedWork W2399086136 @default.
- W149250840 hasRelatedWork W2402218451 @default.
- W149250840 hasRelatedWork W2414027722 @default.
- W149250840 hasVolume "62" @default.
- W149250840 isParatext "false" @default.
- W149250840 isRetracted "false" @default.
- W149250840 magId "149250840" @default.
- W149250840 workType "article" @default.