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- W149277878 abstract "The contribution of genetic factors into the formation of the neurophysiological mechanisms determining the systemic organization of cortical activity has been estimated in 12 pairs of monozygotic (MZ) and 5 pairs of dizygotic (DZ) twins (18–25 years of age). The similarity of individual patterns of the spatial interaction of cortical bioelectric activity measured for different combinations of EEG statistical relationships from 16 monopolar leads has been estimated in each pair of twins and in each of the 544 pairs of unrelated subjects in both groups. The results of the study suggest a high population invariance and small genetic and phenotypic variations of the morphofunctional systems constituting the main neurophysiological mechanisms of general cerebral integration. Brainstem and subcortical regulatory structures play the leading role in the integration of different brain regions into an organized system. Apparently, the formation of these structures during ontogeny follows the same general pattern in all individuals, because deviation from it is likely to affect the fundamental monomorphic characters of the species. The formation of neocortical interregional connections may be expected to exhibit greater individual variation, with the roles of hereditary and environmental factors in the formation of long and relatively short intercortical interactions being different. Apparently, the individual variation of the long intra- and interhemispheric fiber pathways forming the specific morphological framework of the neocortex is largely determined by the genotype. However, the intercentral interactions mediated by short corticocortical connections that are formed in the course of the vital activity of an individual are likely to be mainly determined by the external and internal environments." @default.
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- W149277878 doi "https://doi.org/10.1023/a:1024913020032" @default.
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