Matches in SemOpenAlex for { <https://semopenalex.org/work/W1493256723> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W1493256723 endingPage "1266" @default.
- W1493256723 startingPage "1261" @default.
- W1493256723 abstract "Abstract We have performed experiments to investigate possible physical interactions between C receptors (CR) and surface Ig (sIg) on the B cell plasma membrane. These molecules were found to be independent, non-linked, B cell surface structures, because capping CR1, CR2, sIgM, or sIgD with a specific antibody did not affect the distribution of the remainder of these molecules. Both CR1 and CR2, if bound by antibodies that did not independently cap CR, however, became associated with cross-linked sIg because CR that have been bound by intact anti-CR antibodies or their Fab fragments co-capped with sIgM or sIgD that had been bound by divalent anti-IgM or anti-IgD antibody. CR1 that had bound C3b similarly co-capped with sIg when sIg was cross-linked. Ligand-bound or even cross-linked CR did not associate with non-cross-linked sIg because sIgD, bound by a univalent Fab fragment of anti-IgD antibody, did not co-cap with CR that had been cross-linked by a sandwich of mouse anti-CR antibody and goat anti-mouse Ig. Other surface molecules, such as B1 and HLA-DR Ag, when bound by specific antibodies, did not cap with cross-linked sIg, and sIgD, when bound by a univalent Fab fragment of anti-IgD antibody, did not co-cap with cross-linked sIgM. Interactions between CR and sIg were not mediated by an association with IgG FcR because co-capping of CR and sIg was observed when F(ab')2 fragments of both anti-CR and anti-Ig antibodies were used. These results demonstrate that B cell surface CR can become associated with sIg, but only if sIg is cross-linked and CR is bound by anti-CR antibody or has bound its natural ligand." @default.
- W1493256723 created "2016-06-24" @default.
- W1493256723 creator A5027542245 @default.
- W1493256723 creator A5085992494 @default.
- W1493256723 creator A5088291684 @default.
- W1493256723 creator A5089620562 @default.
- W1493256723 date "1988-08-15" @default.
- W1493256723 modified "2023-10-16" @default.
- W1493256723 title "Ligand-loaded but not free complement receptors for C3b/C4b and C3d co-cap with cross-linked B cell surface IgM and IgD." @default.
- W1493256723 doi "https://doi.org/10.4049/jimmunol.141.4.1261" @default.
- W1493256723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2969399" @default.
- W1493256723 hasPublicationYear "1988" @default.
- W1493256723 type Work @default.
- W1493256723 sameAs 1493256723 @default.
- W1493256723 citedByCount "15" @default.
- W1493256723 countsByYear W14932567232016 @default.
- W1493256723 countsByYear W14932567232017 @default.
- W1493256723 crossrefType "journal-article" @default.
- W1493256723 hasAuthorship W1493256723A5027542245 @default.
- W1493256723 hasAuthorship W1493256723A5085992494 @default.
- W1493256723 hasAuthorship W1493256723A5088291684 @default.
- W1493256723 hasAuthorship W1493256723A5089620562 @default.
- W1493256723 hasBestOaLocation W14932567231 @default.
- W1493256723 hasConcept C116569031 @default.
- W1493256723 hasConcept C153911025 @default.
- W1493256723 hasConcept C159654299 @default.
- W1493256723 hasConcept C170493617 @default.
- W1493256723 hasConcept C178790620 @default.
- W1493256723 hasConcept C185592680 @default.
- W1493256723 hasConcept C203014093 @default.
- W1493256723 hasConcept C2778453870 @default.
- W1493256723 hasConcept C32909587 @default.
- W1493256723 hasConcept C48010095 @default.
- W1493256723 hasConcept C55493867 @default.
- W1493256723 hasConcept C86803240 @default.
- W1493256723 hasConceptScore W1493256723C116569031 @default.
- W1493256723 hasConceptScore W1493256723C153911025 @default.
- W1493256723 hasConceptScore W1493256723C159654299 @default.
- W1493256723 hasConceptScore W1493256723C170493617 @default.
- W1493256723 hasConceptScore W1493256723C178790620 @default.
- W1493256723 hasConceptScore W1493256723C185592680 @default.
- W1493256723 hasConceptScore W1493256723C203014093 @default.
- W1493256723 hasConceptScore W1493256723C2778453870 @default.
- W1493256723 hasConceptScore W1493256723C32909587 @default.
- W1493256723 hasConceptScore W1493256723C48010095 @default.
- W1493256723 hasConceptScore W1493256723C55493867 @default.
- W1493256723 hasConceptScore W1493256723C86803240 @default.
- W1493256723 hasIssue "4" @default.
- W1493256723 hasLocation W14932567231 @default.
- W1493256723 hasLocation W14932567232 @default.
- W1493256723 hasOpenAccess W1493256723 @default.
- W1493256723 hasPrimaryLocation W14932567231 @default.
- W1493256723 hasRelatedWork W1481419192 @default.
- W1493256723 hasRelatedWork W1492718527 @default.
- W1493256723 hasRelatedWork W1654923970 @default.
- W1493256723 hasRelatedWork W1668953894 @default.
- W1493256723 hasRelatedWork W2106553490 @default.
- W1493256723 hasRelatedWork W2107093945 @default.
- W1493256723 hasRelatedWork W2127605373 @default.
- W1493256723 hasRelatedWork W2245764812 @default.
- W1493256723 hasRelatedWork W3022293203 @default.
- W1493256723 hasRelatedWork W4283073772 @default.
- W1493256723 hasVolume "141" @default.
- W1493256723 isParatext "false" @default.
- W1493256723 isRetracted "false" @default.
- W1493256723 magId "1493256723" @default.
- W1493256723 workType "article" @default.