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- W1493306423 abstract "bPurpose of reviewNew developments in the nasal and paranasal sinuscancers are reviewed.Recent findingsIn addition to woodworking, several risk factors for nasaland paranasal sinus cancers have been identified, mostnotably smoking. Progress in the differential diagnosis ofsmall round cell nasal and paranasal sinus cancers allowsthe precise diagnosis of esthesioneuroblastoma. Despiterecent improvements,Tstaging for ethmoid and nasal cavityneeds refinement. An association of surgery and radiationtherapy remains the best treatment modality. Majordevelopments include endoscopic resection of nasal andparanasal sinus cancers, high-precision radiotherapytechniques such as intensity-modulated radiotherapy, andproton-beam radiotherapy. There is probably no role forchemotherapy in esthesioneuroblastoma. Althoughchemotherapy is important for aggressive neoplasms, itsgeneralized use for nasal and paranasal sinus cancersawaits the application/development of newer drugs. Thesedrugs might be applied locally since the majority ofrecurrences remain local.SummaryProgress in the treatment of nasal and paranasal sinuscancers could be achieved through better prevention andthe developments of more selective treatments such asendoscopic resection, high-precision radiotherapy, andnew chemotherapy drugs.Keywordsadenocarcinoma, cancer, craniofacial resection,chemotherapy, esthesioneuroblastoma, epidemiology,endoscopic surgery, neuroectodermal, paranasal sinus,radiotherapy, undifferentiated sinonasal carcinoma" @default.
- W1493306423 created "2016-06-24" @default.
- W1493306423 creator A5015074195 @default.
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- W1493306423 date "2006-04-01" @default.
- W1493306423 modified "2023-09-24" @default.
- W1493306423 title "Nasal and paranasal sinus carcinoma: how can we continue to make progress?" @default.
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