Matches in SemOpenAlex for { <https://semopenalex.org/work/W1493702906> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1493702906 endingPage "368" @default.
- W1493702906 startingPage "354" @default.
- W1493702906 abstract "Horizontal Gene Transfer (HGT) is the event of transferring genetic material from one lineage in the evolutionary tree to a different lineage. HGT plays a major role in bacterial genome diversification and is a significant mechanism by which bacteria develop resistance to antibiotics. Although the prevailing assumption is of complete HGT, cases of partial HGT (which are also named chimeric HGT) where only part of a gene is horizontally transferred, have also been reported, albeit less frequently. In this work we suggest a new probabilistic model for analyzing and modeling phylogenetic networks, the NET-HMM. This new model captures the biologically realistic assumption that neighboring sites of DNA or amino acid sequences are not independent, which increases the accuracy of the inference. The model describes the phylogenetic network as a Hidden Markov Model (HMM), where each hidden state is related to one of the network’s trees. One of the advantages of the NET-HMM is its ability to infer partial HGT as well as complete HGT. We describe the properties of the NET-HMM, devise efficient algorithms for solving a set of problems related to it, and implement them in software. We also provide a novel complementary significance test for evaluating the fitness of a model (NET-HMM) to a given data set. Using NET-HMM we are able to answer interesting biological questions, such as inferring the length of partial HGT’s and the affected nucleotides in the genomic sequences, as well as inferring the exact location of HGT events along the tree branches. These advantages are demonstrated through the analysis of synthetical inputs and two different biological inputs." @default.
- W1493702906 created "2016-06-24" @default.
- W1493702906 creator A5021278923 @default.
- W1493702906 creator A5063493591 @default.
- W1493702906 date "2008-01-01" @default.
- W1493702906 modified "2023-09-25" @default.
- W1493702906 title "Novel Phylogenetic Network Inference by Combining Maximum Likelihood and Hidden Markov Models" @default.
- W1493702906 cites W1513069685 @default.
- W1493702906 cites W1525734744 @default.
- W1493702906 cites W1607036951 @default.
- W1493702906 cites W1776424232 @default.
- W1493702906 cites W1988348433 @default.
- W1493702906 cites W1990812345 @default.
- W1493702906 cites W1992584622 @default.
- W1493702906 cites W1996266138 @default.
- W1493702906 cites W1996387066 @default.
- W1493702906 cites W2004136840 @default.
- W1493702906 cites W2014037171 @default.
- W1493702906 cites W2024811317 @default.
- W1493702906 cites W2038714333 @default.
- W1493702906 cites W2039158827 @default.
- W1493702906 cites W2044530539 @default.
- W1493702906 cites W2049931279 @default.
- W1493702906 cites W2055298722 @default.
- W1493702906 cites W2064794187 @default.
- W1493702906 cites W2097054300 @default.
- W1493702906 cites W2102424972 @default.
- W1493702906 cites W2107062600 @default.
- W1493702906 cites W2113824405 @default.
- W1493702906 cites W2129771418 @default.
- W1493702906 cites W2130675103 @default.
- W1493702906 cites W2132101668 @default.
- W1493702906 cites W2142385590 @default.
- W1493702906 cites W2151742889 @default.
- W1493702906 doi "https://doi.org/10.1007/978-3-540-87361-7_30" @default.
- W1493702906 hasPublicationYear "2008" @default.
- W1493702906 type Work @default.
- W1493702906 sameAs 1493702906 @default.
- W1493702906 citedByCount "0" @default.
- W1493702906 crossrefType "book-chapter" @default.
- W1493702906 hasAuthorship W1493702906A5021278923 @default.
- W1493702906 hasAuthorship W1493702906A5063493591 @default.
- W1493702906 hasBestOaLocation W14937029062 @default.
- W1493702906 hasConcept C104317684 @default.
- W1493702906 hasConcept C113174947 @default.
- W1493702906 hasConcept C134306372 @default.
- W1493702906 hasConcept C154945302 @default.
- W1493702906 hasConcept C177264268 @default.
- W1493702906 hasConcept C193252679 @default.
- W1493702906 hasConcept C199360897 @default.
- W1493702906 hasConcept C23224414 @default.
- W1493702906 hasConcept C26619641 @default.
- W1493702906 hasConcept C2776214188 @default.
- W1493702906 hasConcept C2776817793 @default.
- W1493702906 hasConcept C33923547 @default.
- W1493702906 hasConcept C41008148 @default.
- W1493702906 hasConcept C49937458 @default.
- W1493702906 hasConcept C54355233 @default.
- W1493702906 hasConcept C70721500 @default.
- W1493702906 hasConcept C86803240 @default.
- W1493702906 hasConcept C92938381 @default.
- W1493702906 hasConceptScore W1493702906C104317684 @default.
- W1493702906 hasConceptScore W1493702906C113174947 @default.
- W1493702906 hasConceptScore W1493702906C134306372 @default.
- W1493702906 hasConceptScore W1493702906C154945302 @default.
- W1493702906 hasConceptScore W1493702906C177264268 @default.
- W1493702906 hasConceptScore W1493702906C193252679 @default.
- W1493702906 hasConceptScore W1493702906C199360897 @default.
- W1493702906 hasConceptScore W1493702906C23224414 @default.
- W1493702906 hasConceptScore W1493702906C26619641 @default.
- W1493702906 hasConceptScore W1493702906C2776214188 @default.
- W1493702906 hasConceptScore W1493702906C2776817793 @default.
- W1493702906 hasConceptScore W1493702906C33923547 @default.
- W1493702906 hasConceptScore W1493702906C41008148 @default.
- W1493702906 hasConceptScore W1493702906C49937458 @default.
- W1493702906 hasConceptScore W1493702906C54355233 @default.
- W1493702906 hasConceptScore W1493702906C70721500 @default.
- W1493702906 hasConceptScore W1493702906C86803240 @default.
- W1493702906 hasConceptScore W1493702906C92938381 @default.
- W1493702906 hasLocation W14937029061 @default.
- W1493702906 hasLocation W14937029062 @default.
- W1493702906 hasOpenAccess W1493702906 @default.
- W1493702906 hasPrimaryLocation W14937029061 @default.
- W1493702906 hasRelatedWork W1531451051 @default.
- W1493702906 hasRelatedWork W1537990069 @default.
- W1493702906 hasRelatedWork W1593145341 @default.
- W1493702906 hasRelatedWork W1999357269 @default.
- W1493702906 hasRelatedWork W2065083790 @default.
- W1493702906 hasRelatedWork W2144345157 @default.
- W1493702906 hasRelatedWork W2295960879 @default.
- W1493702906 hasRelatedWork W2964058114 @default.
- W1493702906 hasRelatedWork W4205175008 @default.
- W1493702906 hasRelatedWork W4297918167 @default.
- W1493702906 isParatext "false" @default.
- W1493702906 isRetracted "false" @default.
- W1493702906 magId "1493702906" @default.
- W1493702906 workType "book-chapter" @default.