FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1493771035> ?p ?o ?g. }

• W1493771035 endingPage "132" @default.
• W1493771035 startingPage "124" @default.
• W1493771035 abstract "Abstract Background and Objectives The molecular genetic alterations leading to gastric malignancy are largely unknown. This study aimed to unravel the genomic DNA copy number aberrations (CNAs) profile during gastric tumorigenesis. Methods In this study, we performed genomic profiling in a set of 50 intestinal type gastric carcinomas by a PCR‐based relative quantification method, multiple ligation‐dependent probe amplification (MLPA) with 112 cancer‐related gene loci selected throughout each human chromosome as probes of MLPA assay. Results Numerous chromosomal DNA CNAs, including gains of 3p22, 4q25, 8q24, 11p13, and 20q13, and losses of 1p36 and 9p21, were identified by MLPA assay as recurrent DNA CNAs in gastric cancer. Moreover, we found the median numbers of gains, losses, and total CNAs were significantly higher in lymph node metastasis positive patients than in cases without metastasis. And gain of 11p13 and losses of 9p21.3, 11q13.3, 17q25.3, and 22q11.23 were associated with lymph node metastasis ( P < 0.05). Finally, two major groups, including G1 + 2 with a large number of CNAs and G3 + 4 with a small number of CNAs, can be successfully distinguished by hierarchical cluster analysis. Conclusions Our results proved MLPA is a reliable and efficient method to evaluate DNA copy number changes in gastric cancers. J. Surg. Oncol. 2011; 103:124–132. © 2010 Wiley‐Liss, Inc." @default.
• W1493771035 created "2016-06-24" @default.
• W1493771035 creator A5014979883 @default.
• W1493771035 creator A5033490277 @default.
• W1493771035 creator A5034711230 @default.
• W1493771035 creator A5036590151 @default.
• W1493771035 creator A5069518417 @default.
• W1493771035 creator A5072038316 @default.
• W1493771035 creator A5079974007 @default.
• W1493771035 date "2010-12-22" @default.
• W1493771035 modified "2023-10-10" @default.
• W1493771035 title "Analysis of DNA copy number aberrations by multiple ligation-dependent probe amplification on 50 intestinal type gastric cancers" @default.
• W1493771035 cites W1481143593 @default.
• W1493771035 cites W1526801870 @default.
• W1493771035 cites W1975144873 @default.
• W1493771035 cites W1995832227 @default.
• W1493771035 cites W2013739293 @default.
• W1493771035 cites W2015743742 @default.
• W1493771035 cites W2018035733 @default.
• W1493771035 cites W2029735065 @default.
• W1493771035 cites W2031993038 @default.
• W1493771035 cites W2036708427 @default.
• W1493771035 cites W2044124936 @default.
• W1493771035 cites W2046693410 @default.
• W1493771035 cites W2047939804 @default.
• W1493771035 cites W2048474354 @default.
• W1493771035 cites W2065717886 @default.
• W1493771035 cites W2069614764 @default.
• W1493771035 cites W2071039438 @default.
• W1493771035 cites W2079985291 @default.
• W1493771035 cites W2080043180 @default.
• W1493771035 cites W2081449267 @default.
• W1493771035 cites W2084668940 @default.
• W1493771035 cites W2086359733 @default.
• W1493771035 cites W2113926943 @default.
• W1493771035 cites W2125120607 @default.
• W1493771035 cites W2144154026 @default.
• W1493771035 cites W2249122870 @default.
• W1493771035 cites W2320937221 @default.
• W1493771035 cites W4243379377 @default.
• W1493771035 cites W4255483444 @default.
• W1493771035 doi "https://doi.org/10.1002/jso.21792" @default.
• W1493771035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21259245" @default.
• W1493771035 hasPublicationYear "2010" @default.
• W1493771035 type Work @default.
• W1493771035 sameAs 1493771035 @default.
• W1493771035 citedByCount "15" @default.
• W1493771035 countsByYear W14937710352012 @default.
• W1493771035 countsByYear W14937710352013 @default.
• W1493771035 countsByYear W14937710352014 @default.
• W1493771035 countsByYear W14937710352015 @default.
• W1493771035 countsByYear W14937710352016 @default.
• W1493771035 countsByYear W14937710352020 @default.
• W1493771035 countsByYear W14937710352021 @default.
• W1493771035 crossrefType "journal-article" @default.
• W1493771035 hasAuthorship W1493771035A5014979883 @default.
• W1493771035 hasAuthorship W1493771035A5033490277 @default.
• W1493771035 hasAuthorship W1493771035A5034711230 @default.
• W1493771035 hasAuthorship W1493771035A5036590151 @default.
• W1493771035 hasAuthorship W1493771035A5069518417 @default.
• W1493771035 hasAuthorship W1493771035A5072038316 @default.
• W1493771035 hasAuthorship W1493771035A5079974007 @default.
• W1493771035 hasConcept C104317684 @default.
• W1493771035 hasConcept C120599132 @default.
• W1493771035 hasConcept C120821319 @default.
• W1493771035 hasConcept C121608353 @default.
• W1493771035 hasConcept C124942203 @default.
• W1493771035 hasConcept C126322002 @default.
• W1493771035 hasConcept C141231307 @default.
• W1493771035 hasConcept C143998085 @default.
• W1493771035 hasConcept C17757408 @default.
• W1493771035 hasConcept C2779013556 @default.
• W1493771035 hasConcept C2779399171 @default.
• W1493771035 hasConcept C30481170 @default.
• W1493771035 hasConcept C36823959 @default.
• W1493771035 hasConcept C502942594 @default.
• W1493771035 hasConcept C54355233 @default.
• W1493771035 hasConcept C552990157 @default.
• W1493771035 hasConcept C555283112 @default.
• W1493771035 hasConcept C71924100 @default.
• W1493771035 hasConcept C7602840 @default.
• W1493771035 hasConcept C86803240 @default.
• W1493771035 hasConceptScore W1493771035C104317684 @default.
• W1493771035 hasConceptScore W1493771035C120599132 @default.
• W1493771035 hasConceptScore W1493771035C120821319 @default.
• W1493771035 hasConceptScore W1493771035C121608353 @default.
• W1493771035 hasConceptScore W1493771035C124942203 @default.
• W1493771035 hasConceptScore W1493771035C126322002 @default.
• W1493771035 hasConceptScore W1493771035C141231307 @default.
• W1493771035 hasConceptScore W1493771035C143998085 @default.
• W1493771035 hasConceptScore W1493771035C17757408 @default.
• W1493771035 hasConceptScore W1493771035C2779013556 @default.
• W1493771035 hasConceptScore W1493771035C2779399171 @default.
• W1493771035 hasConceptScore W1493771035C30481170 @default.
• W1493771035 hasConceptScore W1493771035C36823959 @default.
• W1493771035 hasConceptScore W1493771035C502942594 @default.
• W1493771035 hasConceptScore W1493771035C54355233 @default.
• W1493771035 hasConceptScore W1493771035C552990157 @default.

• next