Matches in SemOpenAlex for { <https://semopenalex.org/work/W1493969972> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1493969972 endingPage "316" @default.
- W1493969972 startingPage "312" @default.
- W1493969972 abstract "Tangeretin and nobiletin are polymethoxyflavonoids that are contained in citrus fruits. Polymethoxyflavonoids are reported to have several biological functions including anti-inflammatory, anti-atherogenic, or anti-diabetic effects. However, whether polymethoxyflavonoids directly affect glucose uptake in tissues is not well understood. In the current study, we investigated whether tangeretin and nobiletin affect glucose uptake in insulin target cells such as adipocytes. We observed that treatment with tangeretin or nobiletin significantly increased the uptake of [3H]-deoxyglucose in differentiated 3T3-F442A adipocytes in a concentration-dependent manner. Data showed that phosphatidyl inositol 3 kinase, Akt1/2, and the protein kinase A pathways were involved in the increase in glucose uptake induced by polymethoxyflavonoids. These data suggest that the anti-diabetic action of polymethoxyflavonoids is partly exerted via these signaling pathways in insulin target tissues. Copyright © 2012 John Wiley & Sons, Ltd." @default.
- W1493969972 created "2016-06-24" @default.
- W1493969972 creator A5008660716 @default.
- W1493969972 creator A5017611425 @default.
- W1493969972 creator A5035401647 @default.
- W1493969972 creator A5040543323 @default.
- W1493969972 date "2012-05-14" @default.
- W1493969972 modified "2023-09-26" @default.
- W1493969972 title "Polymethoxyflavonoids Tangeretin and Nobiletin Increase Glucose Uptake in Murine Adipocytes" @default.
- W1493969972 cites W1801085155 @default.
- W1493969972 cites W1968069807 @default.
- W1493969972 cites W1971207228 @default.
- W1493969972 cites W1982621565 @default.
- W1493969972 cites W2000598142 @default.
- W1493969972 cites W2013107200 @default.
- W1493969972 cites W2034039661 @default.
- W1493969972 cites W2038919575 @default.
- W1493969972 cites W2054360790 @default.
- W1493969972 cites W2068545201 @default.
- W1493969972 cites W2074563595 @default.
- W1493969972 cites W2079387502 @default.
- W1493969972 cites W2090771703 @default.
- W1493969972 cites W2096478712 @default.
- W1493969972 cites W2119361109 @default.
- W1493969972 cites W2148792455 @default.
- W1493969972 cites W2154115500 @default.
- W1493969972 cites W2159985671 @default.
- W1493969972 cites W2169799732 @default.
- W1493969972 cites W4237909399 @default.
- W1493969972 doi "https://doi.org/10.1002/ptr.4730" @default.
- W1493969972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22585555" @default.
- W1493969972 hasPublicationYear "2012" @default.
- W1493969972 type Work @default.
- W1493969972 sameAs 1493969972 @default.
- W1493969972 citedByCount "31" @default.
- W1493969972 countsByYear W14939699722013 @default.
- W1493969972 countsByYear W14939699722014 @default.
- W1493969972 countsByYear W14939699722015 @default.
- W1493969972 countsByYear W14939699722016 @default.
- W1493969972 countsByYear W14939699722017 @default.
- W1493969972 countsByYear W14939699722018 @default.
- W1493969972 countsByYear W14939699722019 @default.
- W1493969972 countsByYear W14939699722020 @default.
- W1493969972 countsByYear W14939699722021 @default.
- W1493969972 countsByYear W14939699722022 @default.
- W1493969972 countsByYear W14939699722023 @default.
- W1493969972 crossrefType "journal-article" @default.
- W1493969972 hasAuthorship W1493969972A5008660716 @default.
- W1493969972 hasAuthorship W1493969972A5017611425 @default.
- W1493969972 hasAuthorship W1493969972A5035401647 @default.
- W1493969972 hasAuthorship W1493969972A5040543323 @default.
- W1493969972 hasConcept C126322002 @default.
- W1493969972 hasConcept C134018914 @default.
- W1493969972 hasConcept C184235292 @default.
- W1493969972 hasConcept C185592680 @default.
- W1493969972 hasConcept C2777866211 @default.
- W1493969972 hasConcept C2778004101 @default.
- W1493969972 hasConcept C2778401301 @default.
- W1493969972 hasConcept C2779054382 @default.
- W1493969972 hasConcept C2779306644 @default.
- W1493969972 hasConcept C55493867 @default.
- W1493969972 hasConcept C71924100 @default.
- W1493969972 hasConcept C86803240 @default.
- W1493969972 hasConcept C98274493 @default.
- W1493969972 hasConceptScore W1493969972C126322002 @default.
- W1493969972 hasConceptScore W1493969972C134018914 @default.
- W1493969972 hasConceptScore W1493969972C184235292 @default.
- W1493969972 hasConceptScore W1493969972C185592680 @default.
- W1493969972 hasConceptScore W1493969972C2777866211 @default.
- W1493969972 hasConceptScore W1493969972C2778004101 @default.
- W1493969972 hasConceptScore W1493969972C2778401301 @default.
- W1493969972 hasConceptScore W1493969972C2779054382 @default.
- W1493969972 hasConceptScore W1493969972C2779306644 @default.
- W1493969972 hasConceptScore W1493969972C55493867 @default.
- W1493969972 hasConceptScore W1493969972C71924100 @default.
- W1493969972 hasConceptScore W1493969972C86803240 @default.
- W1493969972 hasConceptScore W1493969972C98274493 @default.
- W1493969972 hasIssue "2" @default.
- W1493969972 hasLocation W14939699721 @default.
- W1493969972 hasLocation W14939699722 @default.
- W1493969972 hasOpenAccess W1493969972 @default.
- W1493969972 hasPrimaryLocation W14939699721 @default.
- W1493969972 hasRelatedWork W1966660296 @default.
- W1493969972 hasRelatedWork W2006513370 @default.
- W1493969972 hasRelatedWork W2089465816 @default.
- W1493969972 hasRelatedWork W2103726562 @default.
- W1493969972 hasRelatedWork W2146199520 @default.
- W1493969972 hasRelatedWork W2155949848 @default.
- W1493969972 hasRelatedWork W2180861891 @default.
- W1493969972 hasRelatedWork W2186867184 @default.
- W1493969972 hasRelatedWork W2398044546 @default.
- W1493969972 hasRelatedWork W3113810870 @default.
- W1493969972 hasVolume "27" @default.
- W1493969972 isParatext "false" @default.
- W1493969972 isRetracted "false" @default.
- W1493969972 magId "1493969972" @default.
- W1493969972 workType "article" @default.