Matches in SemOpenAlex for { <https://semopenalex.org/work/W1494798772> ?p ?o ?g. }
- W1494798772 endingPage "1362" @default.
- W1494798772 startingPage "1355" @default.
- W1494798772 abstract "Abstract: The aim of this study was to examine the effects of the phorbol ester O-tetradecanoylphorbol 13-acetate (TPA) and forskolin on δ-opioid receptor gene transcription. Treatment of NG 108-15 cells with TPA (100 nM) for 48 h increased δ-opioid receptor mRNA levels, whereas different concentrations of forskolin induced a transient down-regulation of mRNA 5 h after treatment, followed by increased mRNA levels after 48 h. Reporter gene assays in transiently transfected NG 108-15 cells in combination with electrophoretic mobility shift assays indicate that the increase of δ-opioid receptor mRNA after stimulation with TPA is mediated by transcription factor AP-1, which binds 355 bp upstream of the start codon within the gene promoter. The forskolin-induced mRNA increase is mediated neither by a cyclic AMP-response element nor indirectly by AP-1 up-regulation. Reporter gene assays, mutational analysis, and electrophoretic mobility shift assays revealed that δ-opioid receptor gene regulation by forskolin is mediated by transcription factor AP-2, which binds to an element 157 bp upstream of the start codon." @default.
- W1494798772 created "2016-06-24" @default.
- W1494798772 creator A5005648435 @default.
- W1494798772 creator A5030937901 @default.
- W1494798772 creator A5033386165 @default.
- W1494798772 date "2002-01-18" @default.
- W1494798772 modified "2023-10-15" @default.
- W1494798772 title "Regulation of Mouse δ-Opioid Receptor Gene Transcription" @default.
- W1494798772 cites W1564556915 @default.
- W1494798772 cites W1954929088 @default.
- W1494798772 cites W1967004332 @default.
- W1494798772 cites W1968800299 @default.
- W1494798772 cites W1982598173 @default.
- W1494798772 cites W1993214904 @default.
- W1494798772 cites W1995277342 @default.
- W1494798772 cites W2000722704 @default.
- W1494798772 cites W2003310921 @default.
- W1494798772 cites W2017867661 @default.
- W1494798772 cites W2018365432 @default.
- W1494798772 cites W2019333488 @default.
- W1494798772 cites W2021052173 @default.
- W1494798772 cites W2025080925 @default.
- W1494798772 cites W2027521767 @default.
- W1494798772 cites W2032216247 @default.
- W1494798772 cites W2039102002 @default.
- W1494798772 cites W2040869898 @default.
- W1494798772 cites W2045112376 @default.
- W1494798772 cites W2053470162 @default.
- W1494798772 cites W2054119130 @default.
- W1494798772 cites W2071253111 @default.
- W1494798772 cites W2071346914 @default.
- W1494798772 cites W2081686001 @default.
- W1494798772 cites W2087078668 @default.
- W1494798772 cites W2088392328 @default.
- W1494798772 cites W2092378185 @default.
- W1494798772 cites W2094109627 @default.
- W1494798772 cites W2112365969 @default.
- W1494798772 cites W2113460448 @default.
- W1494798772 cites W2133747691 @default.
- W1494798772 cites W2143379226 @default.
- W1494798772 cites W2156178535 @default.
- W1494798772 cites W2160066832 @default.
- W1494798772 cites W2188444002 @default.
- W1494798772 cites W2463932359 @default.
- W1494798772 doi "https://doi.org/10.1046/j.1471-4159.2000.0741355.x" @default.
- W1494798772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10737590" @default.
- W1494798772 hasPublicationYear "2002" @default.
- W1494798772 type Work @default.
- W1494798772 sameAs 1494798772 @default.
- W1494798772 citedByCount "24" @default.
- W1494798772 countsByYear W14947987722012 @default.
- W1494798772 countsByYear W14947987722013 @default.
- W1494798772 countsByYear W14947987722016 @default.
- W1494798772 countsByYear W14947987722019 @default.
- W1494798772 countsByYear W14947987722022 @default.
- W1494798772 crossrefType "journal-article" @default.
- W1494798772 hasAuthorship W1494798772A5005648435 @default.
- W1494798772 hasAuthorship W1494798772A5030937901 @default.
- W1494798772 hasAuthorship W1494798772A5033386165 @default.
- W1494798772 hasConcept C101762097 @default.
- W1494798772 hasConcept C104317684 @default.
- W1494798772 hasConcept C105580179 @default.
- W1494798772 hasConcept C132376346 @default.
- W1494798772 hasConcept C138885662 @default.
- W1494798772 hasConcept C150194340 @default.
- W1494798772 hasConcept C153911025 @default.
- W1494798772 hasConcept C161733203 @default.
- W1494798772 hasConcept C1629964 @default.
- W1494798772 hasConcept C170493617 @default.
- W1494798772 hasConcept C179926584 @default.
- W1494798772 hasConcept C183978625 @default.
- W1494798772 hasConcept C185592680 @default.
- W1494798772 hasConcept C195794163 @default.
- W1494798772 hasConcept C2779276759 @default.
- W1494798772 hasConcept C2779886867 @default.
- W1494798772 hasConcept C2780043322 @default.
- W1494798772 hasConcept C2781063702 @default.
- W1494798772 hasConcept C41895202 @default.
- W1494798772 hasConcept C54009773 @default.
- W1494798772 hasConcept C55493867 @default.
- W1494798772 hasConcept C62478195 @default.
- W1494798772 hasConcept C86339819 @default.
- W1494798772 hasConcept C86803240 @default.
- W1494798772 hasConcept C95444343 @default.
- W1494798772 hasConceptScore W1494798772C101762097 @default.
- W1494798772 hasConceptScore W1494798772C104317684 @default.
- W1494798772 hasConceptScore W1494798772C105580179 @default.
- W1494798772 hasConceptScore W1494798772C132376346 @default.
- W1494798772 hasConceptScore W1494798772C138885662 @default.
- W1494798772 hasConceptScore W1494798772C150194340 @default.
- W1494798772 hasConceptScore W1494798772C153911025 @default.
- W1494798772 hasConceptScore W1494798772C161733203 @default.
- W1494798772 hasConceptScore W1494798772C1629964 @default.
- W1494798772 hasConceptScore W1494798772C170493617 @default.
- W1494798772 hasConceptScore W1494798772C179926584 @default.
- W1494798772 hasConceptScore W1494798772C183978625 @default.
- W1494798772 hasConceptScore W1494798772C185592680 @default.
- W1494798772 hasConceptScore W1494798772C195794163 @default.