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- W1495308857 abstract "Reaction of 1, 6-anhydro-2, 2', 3, 4'-tetra-O-benzyl-β-lactose (1, 1 mol eq.) with the acetylated oxazoline of N-acetyllactosamine (2, 5 mol eq.) gave the derivatives of 6'-Nacetyllactosaminyllactose (3, 24.5%) and lacto-N-neohexaose (8, 53.5%). The protecting groups of 3 and 8 were removed by means of the following series of reactions to provide the corresponding tetrasaccharide (7) and hexasaccharide (12), respectively : debenzylation followed by acetylation, acetolysis, and de-O-acetylation. 13C-nuclear magnetic resonance spectral data for the 1, 6-anhydro-β-derivatives of 7 and 12 are presented." @default.
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- W1495308857 date "1981-01-01" @default.
- W1495308857 modified "2023-09-26" @default.
- W1495308857 title "Chemical modification of lactose. XVI. Synthesis of lacto-N-neohexaose." @default.
- W1495308857 doi "https://doi.org/10.1248/cpb.29.587" @default.
- W1495308857 hasPublicationYear "1981" @default.
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