Matches in SemOpenAlex for { <https://semopenalex.org/work/W1495320524> ?p ?o ?g. }
- W1495320524 endingPage "3375" @default.
- W1495320524 startingPage "3370" @default.
- W1495320524 abstract "The enzymes involved in the metabolism of vitamin B6 were measured in Morris hepatomas and livers of female Buffalo rats fed pyridoxine-sufficient and deficient diets. Pyridoxal phosphate levels in plasmas hepatomas, and livers were also determined. Nontumor-bearing animals were maintained as controls. Regardless of the B6 nutritional status, the concentration of pyridoxal phosphate was lower in the hepatomas than in the livers of the host animals. The apoenzyme levels of ornithine decarboxylase, a pyridoxal phosphate-dependent enzyme, were higher in the hepatomas from animals fed the B6-deficient diet. Liver pyridoxine kinase activity was higher in B6-sufficient animals. In contrast, tumor pyridoxine kinase activity was influenced by B6 intake and was significantly lower than that in host liver. Liver pyridoxine phosphate oxidase activity was not significantly affected by B6 intake or by the presence of tumor. In contrast, hepatomas had little or no pyridoxine phosphate oxidase activity. Pyridoxine phosphate phosphatase activity was elevated in tumors relative to livers. These data indicate that the metabolism of vitamin B6 is markedly different in the hepatomas than in host or control livers and suggest that the tumor is apparently incapable of the complete synthesis of co-enzymatically active pyridoxal phosphate from inactive precursor forms such as pyridoxine." @default.
- W1495320524 created "2016-06-24" @default.
- W1495320524 creator A5002921882 @default.
- W1495320524 creator A5036093409 @default.
- W1495320524 creator A5036304588 @default.
- W1495320524 creator A5058028158 @default.
- W1495320524 creator A5088823964 @default.
- W1495320524 date "1981-04-01" @default.
- W1495320524 modified "2023-09-28" @default.
- W1495320524 title "Vitamin B6 metabolism in Morris hepatomas." @default.
- W1495320524 cites W116031781 @default.
- W1495320524 cites W123709287 @default.
- W1495320524 cites W134430268 @default.
- W1495320524 cites W1492989081 @default.
- W1495320524 cites W1512969796 @default.
- W1495320524 cites W1524284319 @default.
- W1495320524 cites W1548712478 @default.
- W1495320524 cites W1554702559 @default.
- W1495320524 cites W1565312099 @default.
- W1495320524 cites W1573775573 @default.
- W1495320524 cites W1580609491 @default.
- W1495320524 cites W1581655281 @default.
- W1495320524 cites W1584198793 @default.
- W1495320524 cites W160040764 @default.
- W1495320524 cites W1608045157 @default.
- W1495320524 cites W1612845612 @default.
- W1495320524 cites W1681535119 @default.
- W1495320524 cites W1775749144 @default.
- W1495320524 cites W1844349716 @default.
- W1495320524 cites W1875054360 @default.
- W1495320524 cites W1879985553 @default.
- W1495320524 cites W1918177285 @default.
- W1495320524 cites W1959423865 @default.
- W1495320524 cites W1964877391 @default.
- W1495320524 cites W1969954079 @default.
- W1495320524 cites W1975187155 @default.
- W1495320524 cites W1981776274 @default.
- W1495320524 cites W1982588383 @default.
- W1495320524 cites W1988463430 @default.
- W1495320524 cites W2009980259 @default.
- W1495320524 cites W2010658459 @default.
- W1495320524 cites W2021456660 @default.
- W1495320524 cites W2023552300 @default.
- W1495320524 cites W2024696207 @default.
- W1495320524 cites W2027716911 @default.
- W1495320524 cites W2033440873 @default.
- W1495320524 cites W2042355431 @default.
- W1495320524 cites W2043354449 @default.
- W1495320524 cites W2052393672 @default.
- W1495320524 cites W2071607988 @default.
- W1495320524 cites W2084974310 @default.
- W1495320524 cites W2085374716 @default.
- W1495320524 cites W2091546906 @default.
- W1495320524 cites W2125110448 @default.
- W1495320524 cites W2150122195 @default.
- W1495320524 cites W2166546987 @default.
- W1495320524 cites W2397487493 @default.
- W1495320524 cites W2403994003 @default.
- W1495320524 cites W2460296029 @default.
- W1495320524 cites W4251137476 @default.
- W1495320524 cites W4323966420 @default.
- W1495320524 cites W72308762 @default.
- W1495320524 cites W959477998 @default.
- W1495320524 doi "https://doi.org/10.1016/s0021-9258(19)69617-1" @default.
- W1495320524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6259164" @default.
- W1495320524 hasPublicationYear "1981" @default.
- W1495320524 type Work @default.
- W1495320524 sameAs 1495320524 @default.
- W1495320524 citedByCount "29" @default.
- W1495320524 countsByYear W14953205242018 @default.
- W1495320524 countsByYear W14953205242020 @default.
- W1495320524 crossrefType "journal-article" @default.
- W1495320524 hasAuthorship W1495320524A5002921882 @default.
- W1495320524 hasAuthorship W1495320524A5036093409 @default.
- W1495320524 hasAuthorship W1495320524A5036304588 @default.
- W1495320524 hasAuthorship W1495320524A5058028158 @default.
- W1495320524 hasAuthorship W1495320524A5088823964 @default.
- W1495320524 hasBestOaLocation W14953205241 @default.
- W1495320524 hasConcept C185592680 @default.
- W1495320524 hasConcept C2776940978 @default.
- W1495320524 hasConcept C3019288012 @default.
- W1495320524 hasConcept C55493867 @default.
- W1495320524 hasConcept C62231903 @default.
- W1495320524 hasConceptScore W1495320524C185592680 @default.
- W1495320524 hasConceptScore W1495320524C2776940978 @default.
- W1495320524 hasConceptScore W1495320524C3019288012 @default.
- W1495320524 hasConceptScore W1495320524C55493867 @default.
- W1495320524 hasConceptScore W1495320524C62231903 @default.
- W1495320524 hasIssue "7" @default.
- W1495320524 hasLocation W14953205241 @default.
- W1495320524 hasOpenAccess W1495320524 @default.
- W1495320524 hasPrimaryLocation W14953205241 @default.
- W1495320524 hasRelatedWork W1492315434 @default.
- W1495320524 hasRelatedWork W1967444479 @default.
- W1495320524 hasRelatedWork W2044802557 @default.
- W1495320524 hasRelatedWork W2113564127 @default.
- W1495320524 hasRelatedWork W2322337089 @default.
- W1495320524 hasRelatedWork W2405984447 @default.