Matches in SemOpenAlex for { <https://semopenalex.org/work/W1495647653> ?p ?o ?g. }
- W1495647653 endingPage "226" @default.
- W1495647653 startingPage "199" @default.
- W1495647653 abstract "There are specific alterations in the structure or function of ion channels in the epileptic brain. Some of these alterations may promote hyperexcitability, whereas others may protect neurons from the deleterious effects of epileptic discharges. With the use of human tissue resected from epilepsy patients and the comparison of cellular properties to those found in well-defined experimental models, we will continue to gain insight into the specific ion channel changes associated with epilepsies. Further genetic studies will help to elucidate the altered molecular mechanisms underlying ion channel changes in this devastating neurological disorder (Noebels, 1996). Whether it is a change in structure, function, or both, the study of ion channels in epilepsies will soon reveal specific characteristics of ion channels found only in epileptic tissue. If the altered properties of such ion channels cannot be found in control (nonepileptic) neurons, these channels might be called epileptic ion channels. An understanding of the specific structure, function, and pharmacology of these epileptic channels will yield important clues for future therapeutical approaches aimed at preventing epileptogenesis, and insight into the processes whereby ion channels become epileptic may finally open the way to prophylactic treatments of the epilepsies." @default.
- W1495647653 created "2016-06-24" @default.
- W1495647653 creator A5017700541 @default.
- W1495647653 date "1998-01-01" @default.
- W1495647653 modified "2023-10-12" @default.
- W1495647653 title "Ion Channels in Epilepsy" @default.
- W1495647653 cites W1214975925 @default.
- W1495647653 cites W1487443352 @default.
- W1495647653 cites W1548516628 @default.
- W1495647653 cites W1603732963 @default.
- W1495647653 cites W1671227548 @default.
- W1495647653 cites W1675918816 @default.
- W1495647653 cites W1772604871 @default.
- W1495647653 cites W1860455432 @default.
- W1495647653 cites W1893829779 @default.
- W1495647653 cites W1944684909 @default.
- W1495647653 cites W1944731016 @default.
- W1495647653 cites W1963764668 @default.
- W1495647653 cites W1966603478 @default.
- W1495647653 cites W1967086231 @default.
- W1495647653 cites W1967696274 @default.
- W1495647653 cites W1968072827 @default.
- W1495647653 cites W1968276667 @default.
- W1495647653 cites W1969155399 @default.
- W1495647653 cites W1970474911 @default.
- W1495647653 cites W1970843014 @default.
- W1495647653 cites W1970907878 @default.
- W1495647653 cites W1971170321 @default.
- W1495647653 cites W1971571944 @default.
- W1495647653 cites W1972459374 @default.
- W1495647653 cites W1972884505 @default.
- W1495647653 cites W1973916261 @default.
- W1495647653 cites W1974324799 @default.
- W1495647653 cites W1974976407 @default.
- W1495647653 cites W1976513474 @default.
- W1495647653 cites W1979198709 @default.
- W1495647653 cites W1982435157 @default.
- W1495647653 cites W1985333845 @default.
- W1495647653 cites W1985525325 @default.
- W1495647653 cites W1988764473 @default.
- W1495647653 cites W1989503595 @default.
- W1495647653 cites W1989938166 @default.
- W1495647653 cites W1990876879 @default.
- W1495647653 cites W1991073933 @default.
- W1495647653 cites W1991647860 @default.
- W1495647653 cites W1991829536 @default.
- W1495647653 cites W1992637683 @default.
- W1495647653 cites W1992950250 @default.
- W1495647653 cites W1994261508 @default.
- W1495647653 cites W1996712322 @default.
- W1495647653 cites W1997419186 @default.
- W1495647653 cites W1997862361 @default.
- W1495647653 cites W1999968276 @default.
- W1495647653 cites W2001112619 @default.
- W1495647653 cites W2002189290 @default.
- W1495647653 cites W2002331174 @default.
- W1495647653 cites W2004159036 @default.
- W1495647653 cites W2005998264 @default.
- W1495647653 cites W2006541920 @default.
- W1495647653 cites W2009297045 @default.
- W1495647653 cites W2010084176 @default.
- W1495647653 cites W2010801705 @default.
- W1495647653 cites W2010923255 @default.
- W1495647653 cites W2012974904 @default.
- W1495647653 cites W2013477495 @default.
- W1495647653 cites W2013520234 @default.
- W1495647653 cites W2016815767 @default.
- W1495647653 cites W2016979211 @default.
- W1495647653 cites W2017329375 @default.
- W1495647653 cites W2017597839 @default.
- W1495647653 cites W2018055706 @default.
- W1495647653 cites W2018883950 @default.
- W1495647653 cites W2018885303 @default.
- W1495647653 cites W2020705596 @default.
- W1495647653 cites W2022924617 @default.
- W1495647653 cites W2023468172 @default.
- W1495647653 cites W2024036641 @default.
- W1495647653 cites W2024105385 @default.
- W1495647653 cites W2024328209 @default.
- W1495647653 cites W2026062374 @default.
- W1495647653 cites W2027552467 @default.
- W1495647653 cites W2028217587 @default.
- W1495647653 cites W2031688286 @default.
- W1495647653 cites W2032950588 @default.
- W1495647653 cites W2034271730 @default.
- W1495647653 cites W2036869107 @default.
- W1495647653 cites W2037174026 @default.
- W1495647653 cites W2037999887 @default.
- W1495647653 cites W2040851668 @default.
- W1495647653 cites W2042307956 @default.
- W1495647653 cites W2045309328 @default.
- W1495647653 cites W2046423382 @default.
- W1495647653 cites W2047735961 @default.
- W1495647653 cites W2048602049 @default.
- W1495647653 cites W2048621600 @default.
- W1495647653 cites W2049001081 @default.
- W1495647653 cites W2049511526 @default.
- W1495647653 cites W2051154442 @default.