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• W1495967840 abstract "To evaluate the error in T1 estimates using inversion-recovery-based T1 mapping due to imperfect inversion and to perform a systematic study of adiabatic inversion pulse designs in order to maximize inversion efficiency for values of transverse relaxation (T2) in the myocardium subject to a peak power constraint.The inversion factor for hyperbolic secant and tangent/hyperbolic tangent adiabatic full passage waveforms was calculated using Bloch equations. A brute-force search was conducted for design parameters: pulse duration, frequency range, shape parameters, and peak amplitude. A design was selected that maximized the inversion factor over a specified range of amplitude and off-resonance and validated using phantom measurements. Empirical correction for imperfect inversion was performed.The tangent/hyperbolic tangent adiabatic pulse was found to outperform hyperbolic secant designs and achieve an inversion factor of 0.96 within ±150 Hz over 25% amplitude range with 14.7 µT peak amplitude. T1 mapping errors of the selected design due to imperfect inversion was ∼4% and could be corrected to <1%.Nonideal inversion leads to significant errors in inversion-recovery-based T1 mapping. The inversion efficiency of adiabatic pulses is sensitive to transverse relaxation. The tangent/hyperbolic tangent design achieved the best performance subject to the peak amplitude constraint." @default.
• W1495967840 created "2016-06-24" @default.
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• W1495967840 date "2013-05-30" @default.
• W1495967840 modified "2023-09-27" @default.
• W1495967840 title "Adiabatic inversion pulses for myocardial T1 mapping" @default.
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• W1495967840 doi "https://doi.org/10.1002/mrm.24793" @default.
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