FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1496007066> ?p ?o ?g. }

• W1496007066 endingPage "256" @default.
• W1496007066 startingPage "248" @default.
• W1496007066 abstract "The aim of the present study was to evaluate the antioxidant potential of embelin in streptozotocin-induced diabetes. Diabetes was induced in rats fasted overnight by the administration of a single dose of streptozotocin, and analyzed for blood, serum, and biological and histological pancreatic tissue parameters in intact control, diabetic, and embelin-treated diabetic rats (n = 9) at the dose levels of 15, 25, and 30 mg/kg/day for 21 days.Diabetes caused highly significant abnormalities in blood, serum, and pancreatic tissue biochemical parameters. Embelin and glibenclamide administration to diabetic rats caused a highly significant decline in the blood glycated hemoglobin and serum glucose levels and nitric oxide activity, with a concomitant increase in the serum insulin level (P < 0.001). Furthermore, embelin and glibenclamide treatment increased the pancreatic antioxidant enzyme status (superoxide dismutase, catalase, reduced glutathione, glutathione peroxidase, glutathione S-transferase, and ascorbic acid), and also decreased the thiobarbituric acid reactive oxygen species contents (P < 0.001). The histoarchitecture of the diabetic rats typically showed a degenerated pancreas with reduced β-cell counts, while embelin treatment was shown to significantly regenerate islet cells.The study proves the potent antioxidant activity of embelin, which has been found to be effective in managing severe hyperglycemia." @default.
• W1496007066 created "2016-06-24" @default.
• W1496007066 creator A5002018692 @default.
• W1496007066 creator A5074837813 @default.
• W1496007066 creator A5076760762 @default.
• W1496007066 creator A5085988586 @default.
• W1496007066 date "2012-08-17" @default.
• W1496007066 modified "2023-10-17" @default.
• W1496007066 title "Antioxidant activity and protection of pancreatic<i>β</i>-cells by embelin in streptozotocin-induced diabetes" @default.
• W1496007066 cites W1572089302 @default.
• W1496007066 cites W172837957 @default.
• W1496007066 cites W183120241 @default.
• W1496007066 cites W1862557020 @default.
• W1496007066 cites W191793640 @default.
• W1496007066 cites W1980667131 @default.
• W1496007066 cites W1980751170 @default.
• W1496007066 cites W1982995596 @default.
• W1496007066 cites W1990089345 @default.
• W1496007066 cites W1994995070 @default.
• W1496007066 cites W1995396857 @default.
• W1496007066 cites W2000617395 @default.
• W1496007066 cites W2001444091 @default.
• W1496007066 cites W2010290591 @default.
• W1496007066 cites W2011683287 @default.
• W1496007066 cites W2012357921 @default.
• W1496007066 cites W2017391549 @default.
• W1496007066 cites W2022952056 @default.
• W1496007066 cites W2026788277 @default.
• W1496007066 cites W2029205714 @default.
• W1496007066 cites W2030726807 @default.
• W1496007066 cites W2042464457 @default.
• W1496007066 cites W2048748542 @default.
• W1496007066 cites W2071577424 @default.
• W1496007066 cites W2072598340 @default.
• W1496007066 cites W2086681284 @default.
• W1496007066 cites W2088866343 @default.
• W1496007066 cites W2115337518 @default.
• W1496007066 cites W2123766698 @default.
• W1496007066 cites W2254746452 @default.
• W1496007066 doi "https://doi.org/10.1111/j.1753-0407.2012.00187.x" @default.
• W1496007066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22252046" @default.
• W1496007066 hasPublicationYear "2012" @default.
• W1496007066 type Work @default.
• W1496007066 sameAs 1496007066 @default.
• W1496007066 citedByCount "43" @default.
• W1496007066 countsByYear W14960070662012 @default.
• W1496007066 countsByYear W14960070662013 @default.
• W1496007066 countsByYear W14960070662014 @default.
• W1496007066 countsByYear W14960070662015 @default.
• W1496007066 countsByYear W14960070662016 @default.
• W1496007066 countsByYear W14960070662017 @default.
• W1496007066 countsByYear W14960070662018 @default.
• W1496007066 countsByYear W14960070662019 @default.
• W1496007066 countsByYear W14960070662020 @default.
• W1496007066 countsByYear W14960070662021 @default.
• W1496007066 countsByYear W14960070662022 @default.
• W1496007066 crossrefType "journal-article" @default.
• W1496007066 hasAuthorship W1496007066A5002018692 @default.
• W1496007066 hasAuthorship W1496007066A5074837813 @default.
• W1496007066 hasAuthorship W1496007066A5076760762 @default.
• W1496007066 hasAuthorship W1496007066A5085988586 @default.
• W1496007066 hasBestOaLocation W14960070661 @default.
• W1496007066 hasConcept C126322002 @default.
• W1496007066 hasConcept C134018914 @default.
• W1496007066 hasConcept C181199279 @default.
• W1496007066 hasConcept C185592680 @default.
• W1496007066 hasConcept C2775838275 @default.
• W1496007066 hasConcept C2776151105 @default.
• W1496007066 hasConcept C2777180221 @default.
• W1496007066 hasConcept C2777538456 @default.
• W1496007066 hasConcept C2778004101 @default.
• W1496007066 hasConcept C2778760513 @default.
• W1496007066 hasConcept C2779280383 @default.
• W1496007066 hasConcept C2779768347 @default.
• W1496007066 hasConcept C2986274086 @default.
• W1496007066 hasConcept C31903555 @default.
• W1496007066 hasConcept C538909803 @default.
• W1496007066 hasConcept C55493867 @default.
• W1496007066 hasConcept C555293320 @default.
• W1496007066 hasConcept C71924100 @default.
• W1496007066 hasConceptScore W1496007066C126322002 @default.
• W1496007066 hasConceptScore W1496007066C134018914 @default.
• W1496007066 hasConceptScore W1496007066C181199279 @default.
• W1496007066 hasConceptScore W1496007066C185592680 @default.
• W1496007066 hasConceptScore W1496007066C2775838275 @default.
• W1496007066 hasConceptScore W1496007066C2776151105 @default.
• W1496007066 hasConceptScore W1496007066C2777180221 @default.
• W1496007066 hasConceptScore W1496007066C2777538456 @default.
• W1496007066 hasConceptScore W1496007066C2778004101 @default.
• W1496007066 hasConceptScore W1496007066C2778760513 @default.
• W1496007066 hasConceptScore W1496007066C2779280383 @default.
• W1496007066 hasConceptScore W1496007066C2779768347 @default.
• W1496007066 hasConceptScore W1496007066C2986274086 @default.
• W1496007066 hasConceptScore W1496007066C31903555 @default.
• W1496007066 hasConceptScore W1496007066C538909803 @default.
• W1496007066 hasConceptScore W1496007066C55493867 @default.
• W1496007066 hasConceptScore W1496007066C555293320 @default.
• W1496007066 hasConceptScore W1496007066C71924100 @default.

• next