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- W1496482529 abstract "Abstract Aim Self‐expandable metallic stents ( SEMS ) have been used for palliation in patients with malignant gastroduodenal obstructions. We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy. Methods A review of records of 85 patients with unresectable gastric or pancreatic cancer who underwent endoscopic SEMS insertion for gastroduodenal obstructions at S eoul N ational U niversity B undang H ospital. Results From A ugust 2003 to O ctober 2009, 85 patients with gastroduodenal obstruction were managed with endoscopic SEMS placement. Technical success was achieved in 82 patients (96%) and clinical success in 68 patients (80%). Of 49 patients who had clinical success, 19 underwent chemotherapy ( chemoTx group), and 30 patients did not ( non‐chemoTx group). Cumulative SEMS patency in the 49 patients who achieved clinical success were 84, 54 and 41% at 2, 3 and 6 months, respectively. By univariate and multivariate analysis, there was no statistical difference in the SEMS patency between the two groups (cumulative SEMS patency rate: 95 vs 73% at 2 months, 15 vs 63% at 3 months, 40 vs 42% at 6 months, respectively, P < 0.793). Conclusion Chemotherapy does not improve SEMS patency in patients with malignant gastroduodenal obstruction caused by unresectable gastric or pancreatic cancer." @default.
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- W1496482529 date "2012-10-11" @default.
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- W1496482529 title "Endoscopic self-expandable metallic stent placement in malignant pyloric or duodenal obstruction: Does chemotherapy affect stent patency?" @default.
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- W1496482529 doi "https://doi.org/10.1111/j.1743-7563.2012.01590.x" @default.
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