Matches in SemOpenAlex for { <https://semopenalex.org/work/W1496641192> ?p ?o ?g. }
- W1496641192 abstract "The intestinal epithelium deploys multiple defense systems against microbial infection to sense bacterial components and danger alarms, as well as to induce intracellular signal transduction cascades that trigger both the innate and the adaptive immune systems, which are pivotal for bacterial elimination. However, many enteric bacterial pathogens, including Shigella, deliver a subset of virulence proteins (effectors) via the type III secretion system (T3SS) that enable bacterial evasion from host immune systems; consequently, these pathogens are able to efficiently colonize the intestinal epithelium. In this review, we present and select recently discovered examples of interactions between Shigella and host immune responses, with particular emphasis on strategies that bacteria use to manipulate inflammatory outputs of host-cell responses such as cell death, membrane trafficking, and innate and adaptive immune responses." @default.
- W1496641192 created "2016-06-24" @default.
- W1496641192 creator A5033408607 @default.
- W1496641192 creator A5036798401 @default.
- W1496641192 creator A5052633242 @default.
- W1496641192 date "2015-05-07" @default.
- W1496641192 modified "2023-10-18" @default.
- W1496641192 title "Shigella Manipulates Host Immune Responses by Delivering Effector Proteins with Specific Roles" @default.
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- W1496641192 doi "https://doi.org/10.3389/fimmu.2015.00219" @default.
- W1496641192 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4423471" @default.
- W1496641192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25999954" @default.
- W1496641192 hasPublicationYear "2015" @default.
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