Matches in SemOpenAlex for { <https://semopenalex.org/work/W1496915816> ?p ?o ?g. }
- W1496915816 endingPage "22787" @default.
- W1496915816 startingPage "22779" @default.
- W1496915816 abstract "We have isolated cDNA clones encoding the entire 170-kDa chain of epiligrin (alpha 3Ep) and a genomic clone encoding the alpha 3Ep gene (LamA3). Analysis of multiple cDNA clones revealed two distinct transcripts (alpha 3EpA and alpha 3EpB). Sequencing of the alpha 3EpA transcript indicated sequence and structural homology to laminin alpha 1 and alpha 2 chains that extend from domain IIIa through the carboxyl-terminal G domain. The alpha 3EpB transcript encodes a larger amino-terminal domain and contains additional epidermal growth factor repeats and sequences corresponding to domain IV of alpha 1 laminin. Fluorescence in situ hybridization indicated that the LamA3 gene is located on chromosome 18q11.2, a locus distinct from the LamA1 gene (18p11.3). The G domain of the epiligrin alpha 3 chain contains five subdomains that are individually related to the G subdomains reported for Drosophila and vertebrate laminin alpha chains. Sequence divergence within the G domain of alpha 3 epiligrin suggests that it is functionally distinct from laminin, consistent with our previous report showing that epiligrin interacts with different integrin adhesion receptors. Analysis of RNA from human foreskin keratinocytes (HFKs) identified multiple epiligrin transcripts that were down-regulated by viral transformation and differentiation. In contrast, epiligrin expression was up-regulated in wound sites of human skin." @default.
- W1496915816 created "2016-06-24" @default.
- W1496915816 creator A5018376808 @default.
- W1496915816 creator A5048352998 @default.
- W1496915816 creator A5051097287 @default.
- W1496915816 creator A5064647006 @default.
- W1496915816 date "1994-09-01" @default.
- W1496915816 modified "2023-10-16" @default.
- W1496915816 title "Cloning of the LamA3 gene encoding the alpha 3 chain of the adhesive ligand epiligrin. Expression in wound repair." @default.
- W1496915816 cites W1501588760 @default.
- W1496915816 cites W1542332509 @default.
- W1496915816 cites W1549235322 @default.
- W1496915816 cites W1552753876 @default.
- W1496915816 cites W1558516755 @default.
- W1496915816 cites W1560452279 @default.
- W1496915816 cites W1563992449 @default.
- W1496915816 cites W157395064 @default.
- W1496915816 cites W1575319966 @default.
- W1496915816 cites W1592892826 @default.
- W1496915816 cites W1628719417 @default.
- W1496915816 cites W1832431561 @default.
- W1496915816 cites W1878446582 @default.
- W1496915816 cites W1894672379 @default.
- W1496915816 cites W1971678284 @default.
- W1496915816 cites W1976288699 @default.
- W1496915816 cites W1981014117 @default.
- W1496915816 cites W1987809783 @default.
- W1496915816 cites W2002453151 @default.
- W1496915816 cites W2009310436 @default.
- W1496915816 cites W2012847227 @default.
- W1496915816 cites W2013803304 @default.
- W1496915816 cites W2014049090 @default.
- W1496915816 cites W2021673452 @default.
- W1496915816 cites W2025018535 @default.
- W1496915816 cites W2025153337 @default.
- W1496915816 cites W2034463149 @default.
- W1496915816 cites W2037973638 @default.
- W1496915816 cites W2045631728 @default.
- W1496915816 cites W2049661143 @default.
- W1496915816 cites W2055043387 @default.
- W1496915816 cites W2062582674 @default.
- W1496915816 cites W2069587384 @default.
- W1496915816 cites W2075965099 @default.
- W1496915816 cites W2079482933 @default.
- W1496915816 cites W2080324921 @default.
- W1496915816 cites W2091970430 @default.
- W1496915816 cites W2093394775 @default.
- W1496915816 cites W2093514870 @default.
- W1496915816 cites W2102193002 @default.
- W1496915816 cites W2105273730 @default.
- W1496915816 cites W2105300288 @default.
- W1496915816 cites W2105516199 @default.
- W1496915816 cites W2106476914 @default.
- W1496915816 cites W2117250276 @default.
- W1496915816 cites W2119622097 @default.
- W1496915816 cites W2122999524 @default.
- W1496915816 cites W2126436520 @default.
- W1496915816 cites W2126741390 @default.
- W1496915816 cites W2133996152 @default.
- W1496915816 cites W2137949057 @default.
- W1496915816 cites W2138270253 @default.
- W1496915816 cites W2138316626 @default.
- W1496915816 cites W2148399778 @default.
- W1496915816 cites W2156411608 @default.
- W1496915816 cites W2169318446 @default.
- W1496915816 cites W2188060873 @default.
- W1496915816 cites W2287070054 @default.
- W1496915816 cites W2398346415 @default.
- W1496915816 cites W4250233718 @default.
- W1496915816 doi "https://doi.org/10.1016/s0021-9258(17)31713-1" @default.
- W1496915816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8077230" @default.
- W1496915816 hasPublicationYear "1994" @default.
- W1496915816 type Work @default.
- W1496915816 sameAs 1496915816 @default.
- W1496915816 citedByCount "258" @default.
- W1496915816 countsByYear W14969158162012 @default.
- W1496915816 countsByYear W14969158162013 @default.
- W1496915816 countsByYear W14969158162014 @default.
- W1496915816 countsByYear W14969158162015 @default.
- W1496915816 countsByYear W14969158162016 @default.
- W1496915816 countsByYear W14969158162017 @default.
- W1496915816 countsByYear W14969158162018 @default.
- W1496915816 countsByYear W14969158162019 @default.
- W1496915816 countsByYear W14969158162020 @default.
- W1496915816 countsByYear W14969158162021 @default.
- W1496915816 countsByYear W14969158162022 @default.
- W1496915816 countsByYear W14969158162023 @default.
- W1496915816 crossrefType "journal-article" @default.
- W1496915816 hasAuthorship W1496915816A5018376808 @default.
- W1496915816 hasAuthorship W1496915816A5048352998 @default.
- W1496915816 hasAuthorship W1496915816A5051097287 @default.
- W1496915816 hasAuthorship W1496915816A5064647006 @default.
- W1496915816 hasBestOaLocation W14969158161 @default.
- W1496915816 hasConcept C104317684 @default.
- W1496915816 hasConcept C121050878 @default.
- W1496915816 hasConcept C141071460 @default.
- W1496915816 hasConcept C150194340 @default.
- W1496915816 hasConcept C153911025 @default.