FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1497080962> ?p ?o ?g. }

• W1497080962 endingPage "1487" @default.
• W1497080962 startingPage "1480" @default.
• W1497080962 abstract "Neoadjuvant chemotherapy is able to reduce the size of the majority of breast tumours and down-stage axillary-node status. The aim of this study was to assess the prognostic value of persistent node involvement after neoadjuvant chemotherapy. A total of 488 patients with T2-T3, N0-N1 breast cancer treated by neoadjuvant chemotherapy followed by tumour excision and axillary lymph-node dissection between 1981 and 1992 were selected from the Institut Curie database. Median follow-up was 7 years. Overall objective response rate before local treatment was 52% and breast tumour size was reduced in 83% of patients. No pathologic nodal involvement was observed in 46. 5% of patients. Patients with > or = eight positive nodes had a very poor median disease-free survival of only 20 months. Their 10-year disease-free survival rate was 7%, while the 10-year disease-free survival rate for patients with no node involvement was 64%. Median survival for patients with > or = eight nodes positive was 48 months and the 10-year survival rate was 26% (P < 0.0001). On multivariate analysis, outcome was strongly correlated with pathological nodal status, tumour grade, hormonal receptor status and clinical response of the tumour. In conclusion, patients with extensive nodal involvement after neoadjuvant chemotherapy have a very poor outcome. Second-line treatment should be considered in this population." @default.
• W1497080962 created "2016-06-24" @default.
• W1497080962 creator A5015202957 @default.
• W1497080962 creator A5018736489 @default.
• W1497080962 creator A5026180389 @default.
• W1497080962 creator A5037340510 @default.
• W1497080962 creator A5040169353 @default.
• W1497080962 creator A5048550270 @default.
• W1497080962 creator A5051839713 @default.
• W1497080962 creator A5056565799 @default.
• W1497080962 creator A5068413883 @default.
• W1497080962 creator A5075230685 @default.
• W1497080962 creator A5075286178 @default.
• W1497080962 creator A5085752463 @default.
• W1497080962 creator A5091592799 @default.
• W1497080962 date "2000-12-01" @default.
• W1497080962 modified "2023-10-06" @default.
• W1497080962 title "Prognostic value of persistent node involvement after neoadjuvant chemotherapy in patients with operable breast cancer" @default.
• W1497080962 cites W12086493 @default.
• W1497080962 cites W122589447 @default.
• W1497080962 cites W139042253 @default.
• W1497080962 cites W151574441 @default.
• W1497080962 cites W1754020298 @default.
• W1497080962 cites W1949597673 @default.
• W1497080962 cites W1955397179 @default.
• W1497080962 cites W1962197769 @default.
• W1497080962 cites W1972637700 @default.
• W1497080962 cites W1985495442 @default.
• W1497080962 cites W1999480135 @default.
• W1497080962 cites W2006749087 @default.
• W1497080962 cites W2009982289 @default.
• W1497080962 cites W2016375234 @default.
• W1497080962 cites W2020321814 @default.
• W1497080962 cites W2025319947 @default.
• W1497080962 cites W2026686462 @default.
• W1497080962 cites W2052025976 @default.
• W1497080962 cites W2062421538 @default.
• W1497080962 cites W2069006094 @default.
• W1497080962 cites W2076462903 @default.
• W1497080962 cites W2076668534 @default.
• W1497080962 cites W2081836979 @default.
• W1497080962 cites W2096602429 @default.
• W1497080962 cites W2124111162 @default.
• W1497080962 cites W2133764807 @default.
• W1497080962 cites W2138021040 @default.
• W1497080962 cites W2139510434 @default.
• W1497080962 cites W2139984188 @default.
• W1497080962 cites W2161897297 @default.
• W1497080962 cites W2248496925 @default.
• W1497080962 cites W2287271371 @default.
• W1497080962 cites W2335018892 @default.
• W1497080962 cites W2411591675 @default.
• W1497080962 cites W2440847557 @default.
• W1497080962 cites W2994097899 @default.
• W1497080962 cites W2116301188 @default.
• W1497080962 doi "https://doi.org/10.1054/bjoc.2000.1461" @default.
• W1497080962 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2363409" @default.
• W1497080962 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11076657" @default.
• W1497080962 hasPublicationYear "2000" @default.
• W1497080962 type Work @default.
• W1497080962 sameAs 1497080962 @default.
• W1497080962 citedByCount "121" @default.
• W1497080962 countsByYear W14970809622012 @default.
• W1497080962 countsByYear W14970809622013 @default.
• W1497080962 countsByYear W14970809622014 @default.
• W1497080962 countsByYear W14970809622015 @default.
• W1497080962 countsByYear W14970809622016 @default.
• W1497080962 countsByYear W14970809622017 @default.
• W1497080962 countsByYear W14970809622018 @default.
• W1497080962 countsByYear W14970809622019 @default.
• W1497080962 countsByYear W14970809622020 @default.
• W1497080962 countsByYear W14970809622021 @default.
• W1497080962 countsByYear W14970809622023 @default.
• W1497080962 crossrefType "journal-article" @default.
• W1497080962 hasAuthorship W1497080962A5015202957 @default.
• W1497080962 hasAuthorship W1497080962A5018736489 @default.
• W1497080962 hasAuthorship W1497080962A5026180389 @default.
• W1497080962 hasAuthorship W1497080962A5037340510 @default.
• W1497080962 hasAuthorship W1497080962A5040169353 @default.
• W1497080962 hasAuthorship W1497080962A5048550270 @default.
• W1497080962 hasAuthorship W1497080962A5051839713 @default.
• W1497080962 hasAuthorship W1497080962A5056565799 @default.
• W1497080962 hasAuthorship W1497080962A5068413883 @default.
• W1497080962 hasAuthorship W1497080962A5075230685 @default.
• W1497080962 hasAuthorship W1497080962A5075286178 @default.
• W1497080962 hasAuthorship W1497080962A5085752463 @default.
• W1497080962 hasAuthorship W1497080962A5091592799 @default.
• W1497080962 hasBestOaLocation W14970809621 @default.
• W1497080962 hasConcept C121608353 @default.
• W1497080962 hasConcept C126322002 @default.
• W1497080962 hasConcept C141071460 @default.
• W1497080962 hasConcept C143998085 @default.
• W1497080962 hasConcept C146357865 @default.
• W1497080962 hasConcept C151730666 @default.
• W1497080962 hasConcept C2776283816 @default.
• W1497080962 hasConcept C2776608951 @default.
• W1497080962 hasConcept C2776694085 @default.
• W1497080962 hasConcept C2778292576 @default.

• next