Matches in SemOpenAlex for { <https://semopenalex.org/work/W1497138019> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- W1497138019 endingPage "914" @default.
- W1497138019 startingPage "913" @default.
- W1497138019 abstract "One of the drawbacks of the slew of anti-mitotic drugs that are used to treat cancer is that they all target the assembly or disassembly of tubulin, the molecular building block of microtubules. By disrupting the polymerization of tubulin into microtubules, which are the essential components of the mitotic spindle without which mitosis cannot proceed, these drugs are able to inhibit the cell cycle. In a Perspective, Duane Compton discusses a new screening method that identifies anti-mitotic drugs that target components of the spindle other than tubulin. These compounds should prove valuable both in elucidating the different steps in spindle assembly and as the basis of a new class of anticancer agents." @default.
- W1497138019 created "2016-06-24" @default.
- W1497138019 creator A5018621864 @default.
- W1497138019 date "1999-10-29" @default.
- W1497138019 modified "2023-10-18" @default.
- W1497138019 title "New Tools for the Antimitotic Toolbox" @default.
- W1497138019 cites W1988369885 @default.
- W1497138019 cites W2007928608 @default.
- W1497138019 cites W2029178312 @default.
- W1497138019 cites W2042215748 @default.
- W1497138019 cites W2046422813 @default.
- W1497138019 cites W2062771754 @default.
- W1497138019 doi "https://doi.org/10.1126/science.286.5441.913" @default.
- W1497138019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10577242" @default.
- W1497138019 hasPublicationYear "1999" @default.
- W1497138019 type Work @default.
- W1497138019 sameAs 1497138019 @default.
- W1497138019 citedByCount "6" @default.
- W1497138019 countsByYear W14971380192022 @default.
- W1497138019 crossrefType "journal-article" @default.
- W1497138019 hasAuthorship W1497138019A5018621864 @default.
- W1497138019 hasConcept C199360897 @default.
- W1497138019 hasConcept C2777655017 @default.
- W1497138019 hasConcept C41008148 @default.
- W1497138019 hasConcept C70721500 @default.
- W1497138019 hasConcept C86803240 @default.
- W1497138019 hasConceptScore W1497138019C199360897 @default.
- W1497138019 hasConceptScore W1497138019C2777655017 @default.
- W1497138019 hasConceptScore W1497138019C41008148 @default.
- W1497138019 hasConceptScore W1497138019C70721500 @default.
- W1497138019 hasConceptScore W1497138019C86803240 @default.
- W1497138019 hasIssue "5441" @default.
- W1497138019 hasLocation W14971380191 @default.
- W1497138019 hasLocation W14971380192 @default.
- W1497138019 hasOpenAccess W1497138019 @default.
- W1497138019 hasPrimaryLocation W14971380191 @default.
- W1497138019 hasRelatedWork W1981737222 @default.
- W1497138019 hasRelatedWork W2324336873 @default.
- W1497138019 hasRelatedWork W2353433747 @default.
- W1497138019 hasRelatedWork W2617852013 @default.
- W1497138019 hasRelatedWork W2724830044 @default.
- W1497138019 hasRelatedWork W2748952813 @default.
- W1497138019 hasRelatedWork W2899084033 @default.
- W1497138019 hasRelatedWork W2913244869 @default.
- W1497138019 hasRelatedWork W3118380721 @default.
- W1497138019 hasRelatedWork W4256182355 @default.
- W1497138019 hasVolume "286" @default.
- W1497138019 isParatext "false" @default.
- W1497138019 isRetracted "false" @default.
- W1497138019 magId "1497138019" @default.
- W1497138019 workType "article" @default.