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• W1497153995 abstract "This chapter discusses the functional organization of the brain in chronic pain. The chapter focuses on cortical reorganization and chronic pain. It also discusses the role of pain memories in primary and associative cortex. The chapter summarizes the findings on cortical reorganization and phantom limb pain. Cortical reorganization describes functional and structural changes in the representational maps of the sensory and motor areas of adult mammals related to an altered efficacy of sensory inputs, to changes in the availability of effecters or due to injury. The chapter examines, to what extent operant learning also influences brain responses related to the processing of nociceptive input. Cortical reorganization also seems to play an important role in another type of pain that has remained an enigma— phantom limb pain. The prevention of somatosensory pain memories is important and might be accomplished by (a) the prevention of chronic pain and thus cortical reorganization by pharmacological and psychological interventions in order to make sure that pain memories are not being established and (b) cortical reorganization related to amputation could further be prevented by giving N-Methyl-D-aspartate antagonists and/or gamma-aminobutyric acid agonists prior to and after the surgery." @default.
• W1497153995 created "2016-06-24" @default.
• W1497153995 creator A5030737970 @default.
• W1497153995 date "2000-01-01" @default.
• W1497153995 modified "2023-10-14" @default.
• W1497153995 title "The functional organization of the brain in chronic pain" @default.
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• W1497153995 doi "https://doi.org/10.1016/s0079-6123(00)29023-7" @default.
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