Matches in SemOpenAlex for { <https://semopenalex.org/work/W1497450123> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1497450123 endingPage "329" @default.
- W1497450123 startingPage "322" @default.
- W1497450123 abstract "Prader-Willi syndrome is characterized by infantile hypotonia, mental retardation, hyperphagia with obesity, and hypogonadism. Three affected male patients, ages nineteen, twenty and twenty-three, were found to have hypogonadotropic hypogonadism. Pituitary function was otherwise normal. Testicular biopsy revealed prepubertal tubules with abnormalities of interstitial tissue in one patient and arrest of tubular development in another. One patient was treated with clomiphene citrate for forty days and plasma luteinizing hormone (LH), testosterone and urinary gonadotropin levels rose to the normal range for males. These hormonal levels remained normal for at least eighty days after treatment was stopped. Normal Spermatogenesis was present on repeat testicular biopsy, and physical signs of puberty were evident. Hypogonadism in Prader-Willi syndrome appears to be the result of hypothalamic dysfunction. Clomiphene citrate may be effective treatment for male hypogonadism in this syndrome." @default.
- W1497450123 created "2016-06-24" @default.
- W1497450123 creator A5035731826 @default.
- W1497450123 creator A5037175015 @default.
- W1497450123 creator A5082570132 @default.
- W1497450123 date "1972-03-01" @default.
- W1497450123 modified "2023-10-16" @default.
- W1497450123 title "Hypogonadotropinism in Prader-Willi syndrome" @default.
- W1497450123 cites W1993582954 @default.
- W1497450123 cites W1994469751 @default.
- W1497450123 cites W2005038318 @default.
- W1497450123 cites W2041775104 @default.
- W1497450123 cites W2051409595 @default.
- W1497450123 cites W2056937976 @default.
- W1497450123 cites W2086113818 @default.
- W1497450123 cites W2089508892 @default.
- W1497450123 cites W2092717550 @default.
- W1497450123 cites W2149959392 @default.
- W1497450123 cites W2168653185 @default.
- W1497450123 cites W2171795271 @default.
- W1497450123 cites W2345713365 @default.
- W1497450123 cites W2399564881 @default.
- W1497450123 cites W2408075998 @default.
- W1497450123 cites W2427828158 @default.
- W1497450123 doi "https://doi.org/10.1016/0002-9343(72)90019-8" @default.
- W1497450123 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5011391" @default.
- W1497450123 hasPublicationYear "1972" @default.
- W1497450123 type Work @default.
- W1497450123 sameAs 1497450123 @default.
- W1497450123 citedByCount "59" @default.
- W1497450123 countsByYear W14974501232014 @default.
- W1497450123 countsByYear W14974501232015 @default.
- W1497450123 countsByYear W14974501232016 @default.
- W1497450123 countsByYear W14974501232020 @default.
- W1497450123 countsByYear W14974501232022 @default.
- W1497450123 crossrefType "journal-article" @default.
- W1497450123 hasAuthorship W1497450123A5035731826 @default.
- W1497450123 hasAuthorship W1497450123A5037175015 @default.
- W1497450123 hasAuthorship W1497450123A5082570132 @default.
- W1497450123 hasConcept C123765429 @default.
- W1497450123 hasConcept C126322002 @default.
- W1497450123 hasConcept C134018914 @default.
- W1497450123 hasConcept C2775934546 @default.
- W1497450123 hasConcept C2776354409 @default.
- W1497450123 hasConcept C2777423934 @default.
- W1497450123 hasConcept C2778575703 @default.
- W1497450123 hasConcept C2779279991 @default.
- W1497450123 hasConcept C2779546488 @default.
- W1497450123 hasConcept C2780302854 @default.
- W1497450123 hasConcept C2781255401 @default.
- W1497450123 hasConcept C71315377 @default.
- W1497450123 hasConcept C71924100 @default.
- W1497450123 hasConceptScore W1497450123C123765429 @default.
- W1497450123 hasConceptScore W1497450123C126322002 @default.
- W1497450123 hasConceptScore W1497450123C134018914 @default.
- W1497450123 hasConceptScore W1497450123C2775934546 @default.
- W1497450123 hasConceptScore W1497450123C2776354409 @default.
- W1497450123 hasConceptScore W1497450123C2777423934 @default.
- W1497450123 hasConceptScore W1497450123C2778575703 @default.
- W1497450123 hasConceptScore W1497450123C2779279991 @default.
- W1497450123 hasConceptScore W1497450123C2779546488 @default.
- W1497450123 hasConceptScore W1497450123C2780302854 @default.
- W1497450123 hasConceptScore W1497450123C2781255401 @default.
- W1497450123 hasConceptScore W1497450123C71315377 @default.
- W1497450123 hasConceptScore W1497450123C71924100 @default.
- W1497450123 hasIssue "3" @default.
- W1497450123 hasLocation W14974501231 @default.
- W1497450123 hasLocation W14974501232 @default.
- W1497450123 hasOpenAccess W1497450123 @default.
- W1497450123 hasPrimaryLocation W14974501231 @default.
- W1497450123 hasRelatedWork W1988486434 @default.
- W1497450123 hasRelatedWork W1999611386 @default.
- W1497450123 hasRelatedWork W1999831221 @default.
- W1497450123 hasRelatedWork W2012502375 @default.
- W1497450123 hasRelatedWork W2047880909 @default.
- W1497450123 hasRelatedWork W2064034534 @default.
- W1497450123 hasRelatedWork W2073502422 @default.
- W1497450123 hasRelatedWork W2122048062 @default.
- W1497450123 hasRelatedWork W2163989763 @default.
- W1497450123 hasRelatedWork W2313856518 @default.
- W1497450123 hasVolume "52" @default.
- W1497450123 isParatext "false" @default.
- W1497450123 isRetracted "false" @default.
- W1497450123 magId "1497450123" @default.
- W1497450123 workType "article" @default.