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- W1497487597 abstract "Objectives: Sepsis in critical illness is associated with the progressive failure of multiple organs. Additional biomarkers in severe sepsis are needed to tackle the challenges of determining a prognosis and optimizing the selection of high-risk patients for therapy. This paper evaluates serum C-reactive protein (CRP) and amylase as prognostic factors for survival in patients with severe sepsis. Patients and Methods: Ninety-five patients (42 males, 53 females) meeting the criteria for severe sepsis were chosen for the study. APACHE II scores, serum levels of CRP and amylase were taken on admission to an intensive care unit, two days later, and on the day of discharge from the intensive care unit or on the day of death. Results: Amylase levels, median CRP levels, and APACHE II scores were significantly higher in the non-survivors than in the surviving patients. Conclusion: Serum amylase and CRP are predictors of survival in patients with severe sepsis. High amylase and CRP levels appear to be a valuable tool for individual risk assessment in severe sepsis patients and for stratification of high-risk patients in future intervention trials. Turkish Baslik: Pankreatik Olmayan Agir Sepsisli Hastalarda Belirleyici Faktorler Olarak Yuksek C-Reaktif Protein ve Amilaz Degerleri Anahtar Kelimeler: C-reaktif protein; amilaz; prognostik faktor; agir sepsis Amac: Kritik hastalarda sepsis ilerleyen multi organ yetmezligi ile iliskilidir. Agir sepsiste ilave biyogostergeler, yuksek riskli hastalarin etkili tedavi seciminde ve prognozun belirlenmesi mucadelesinde basarili olmak icin gereklidir. Bu arastirmada agir sepsisli hastalarda sagkalim icin belirleyici faktorler olarak serumda C-reaktif protein (CRP) ve amilaz degerlendirildi. Hastalar ve Yontemler: Calismaya agir sepsis kriterlerini saglayan 95 hasta (42 erkek, 53 kadin) dahil edildi. APACHE II skorlari, serum CRP ve amilaz duzeyleri hastalarin yogun bakim unitesine kabul edildiginde, iki gun sonra ve yogun bakim unitesinden taburcu edildigi gun veya kaybedildikleri gun alindi. Bulgular: Amilaz ve ortalama CRP duzeyleri ile APACHE II skorlari yasamini kaybeden hastalarda, sag kalan hastalardan anlamli derecede yuksekti. Sonuc: Serum amilaz ve CRP, agir sepsisli hastalarda sagkalimi belirleyicidir. Yuksek amilaz ve CRP duzeyleri agir sepsisli hastalarin risk degerlendirmesinde ve gelecek calismalarda yuksek riskli hastalarin siniflandirilmasinda degerli araclar olarak gorulebilir." @default.
- W1497487597 created "2016-06-24" @default.
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- W1497487597 date "2009-01-01" @default.
- W1497487597 modified "2023-09-27" @default.
- W1497487597 title "High C-Reactive Protein and Amylase Levels as Prognostic Markers in Non-Pancreatic Severe Sepsis Patients" @default.
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