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- W1497505325 abstract "Summary. The effect of pyridoxal-5-phosphate, δ-aminolaevulinic acid and haematin hydrochloride on the in-vitro synthesis of globin by reticulocytes has been examined in sideroblastic anaemia. In each of the seven patients studied, haematin consistently stimulated globin synthesis. In two siblings suffering from congenital sideroblastic anaemia δ-ALA also stimulated globin synthesis. It was, however, ineffective in another patient with the same disorder with different clinical and haematological features. This evidence strongly supports our earlier conclusions that sideroblastic anaemia is brought about by a deficiency of haem. It also demonstrates biochemical heterogenity in the congenital type of sideroblastic anaemia." @default.
- W1497505325 created "2016-06-24" @default.
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- W1497505325 date "1973-04-01" @default.
- W1497505325 modified "2023-10-05" @default.
- W1497505325 title "Globin Synthesis in Sideroblastic Anaemia." @default.
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- W1497505325 doi "https://doi.org/10.1111/j.1365-2141.1973.tb01674.x" @default.
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