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• W1497679 abstract "Historically, biosensors were initially developed for the control of diabetes by quantitatively determining glucose levels in the blood of humans. The ease of biosensor use has prompted and permitted the application of this device for the detection of analytes that are involved in other diseases. Biosensors are being used increasingly nowadays for the management, control, and diagnosis of a wide variety of diseases. Some of the more recent applications of the detection by biosensors of disease-related analytes that have recently appeared in the literature are also outlined in this chapter. Binding and dissociation (if applicable) kinetic curves for the examples mentioned are taken from the literature and analyzed using fractal methods to help determine binding and dissociation (if applicable) rate coefficient(s) values, as well as values of the fractal dimensions present in the binding and dissociation (if applicable) phases. Affinity values are also of interest to practicing biosensorists, and these values are also presented. A fractal analysis is presented for the binding of different analytes in solution that help control diseases on biosensor surfaces. The fractal analysis provides values of the binding rate coefficient between the analyte (in solution)–receptor (on the surface) interactions occurring on biosensor surfaces and the fractal dimension, D f, which provides an indication of the degree of heterogeneity on the biosensor surface. The fractal analysis is offered as an alternate way to improve the understanding of the kinetics in the heterogeneous case with the diffusion-limited reactions occurring on structured surfaces." @default.
• W1497679 created "2016-06-24" @default.
• W1497679 creator A5037016654 @default.
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• W1497679 date "2008-01-01" @default.
• W1497679 modified "2023-09-26" @default.
• W1497679 title "Fractal Analysis of Binding and Dissociation of Analytes that Help Control Diseases on Biosensor Surfaces" @default.
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• W1497679 doi "https://doi.org/10.1016/b978-044453010-3.50007-4" @default.
• W1497679 hasPublicationYear "2008" @default.
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