Matches in SemOpenAlex for { <https://semopenalex.org/work/W1497751585> ?p ?o ?g. }
- W1497751585 endingPage "190" @default.
- W1497751585 startingPage "149" @default.
- W1497751585 abstract "This review discusses the ways in which comparative genomics can contribute to the study of fish endocrinology. First, the phylogenetic position of fish and an overview of their specific endocrine systems are presented. The emphasis will be on teleosts because they are the most abundant fishes and because most data are available for this group. Second, the complexity of fish genomics is reviewed. With the vast array of genome sizes and pioidy levels, assignment of gene orthology is more difficult in fish, but this is an absolute prerequisite in functional analysis and it is important to be aware of such genome plasticity when cloning genes. The ease with which a gene is cloned at the genomic level is directly related to genome size and complexity, a factor that is not known in the majority of fish species. Finally, the methodology is presented along with specific examples of parathyroid hormone-related protein (PTHrP) (a previously unidentified hormone in fish), calcium-sensing receptor, and calcitonin (with a duplication of this particular ligand in Fugu rubripes). Preliminary data also suggest that there are further duplicated genes in the calcium regulatory system. Comparative genomics has provided a valuable approach for isolating and characterizing a range of fish genes involved in calcium regulation. However, for understanding the physiology and endocrine regulation of this system, particularly with regard to gene duplication, an alternative approach is required in which conventional endocrinology techniques will play a significant role." @default.
- W1497751585 created "2016-06-24" @default.
- W1497751585 creator A5015482665 @default.
- W1497751585 creator A5017375663 @default.
- W1497751585 creator A5050593613 @default.
- W1497751585 date "2002-01-01" @default.
- W1497751585 modified "2023-09-25" @default.
- W1497751585 title "Application of comparative genomics in fish endocrinology" @default.
- W1497751585 cites W1485026663 @default.
- W1497751585 cites W1509338398 @default.
- W1497751585 cites W1528605131 @default.
- W1497751585 cites W1545009729 @default.
- W1497751585 cites W1552701438 @default.
- W1497751585 cites W1595268720 @default.
- W1497751585 cites W1606232948 @default.
- W1497751585 cites W1631443965 @default.
- W1497751585 cites W1692307837 @default.
- W1497751585 cites W1913751214 @default.
- W1497751585 cites W1932232911 @default.
- W1497751585 cites W1963933110 @default.
- W1497751585 cites W1964251185 @default.
- W1497751585 cites W1965142337 @default.
- W1497751585 cites W1965950801 @default.
- W1497751585 cites W1966121053 @default.
- W1497751585 cites W1966960775 @default.
- W1497751585 cites W1967025078 @default.
- W1497751585 cites W1967585087 @default.
- W1497751585 cites W1968736614 @default.
- W1497751585 cites W1970835368 @default.
- W1497751585 cites W1976015725 @default.
- W1497751585 cites W1976572298 @default.
- W1497751585 cites W1978082643 @default.
- W1497751585 cites W1978656608 @default.
- W1497751585 cites W1985661587 @default.
- W1497751585 cites W1987375466 @default.
- W1497751585 cites W1994135457 @default.
- W1497751585 cites W1994210709 @default.
- W1497751585 cites W1999806767 @default.
- W1497751585 cites W2002426641 @default.
- W1497751585 cites W2003006518 @default.
- W1497751585 cites W2004919558 @default.
- W1497751585 cites W2010798525 @default.
- W1497751585 cites W2011130846 @default.
- W1497751585 cites W2014583348 @default.
- W1497751585 cites W2015633789 @default.
- W1497751585 cites W2015691867 @default.
- W1497751585 cites W2017211434 @default.
- W1497751585 cites W2022257217 @default.
- W1497751585 cites W2023047947 @default.
- W1497751585 cites W2023076340 @default.
- W1497751585 cites W2023743517 @default.
- W1497751585 cites W2027241056 @default.
- W1497751585 cites W2027549079 @default.
- W1497751585 cites W2030206451 @default.
- W1497751585 cites W2032212421 @default.
- W1497751585 cites W2033066280 @default.
- W1497751585 cites W2034473596 @default.
- W1497751585 cites W2035169517 @default.
- W1497751585 cites W2036775128 @default.
- W1497751585 cites W2039182016 @default.
- W1497751585 cites W2040303265 @default.
- W1497751585 cites W2044374245 @default.
- W1497751585 cites W2046438595 @default.
- W1497751585 cites W2047042023 @default.
- W1497751585 cites W2047428960 @default.
- W1497751585 cites W2047693103 @default.
- W1497751585 cites W2049642777 @default.
- W1497751585 cites W2050538166 @default.
- W1497751585 cites W2054468001 @default.
- W1497751585 cites W2055332319 @default.
- W1497751585 cites W2055345648 @default.
- W1497751585 cites W2056537262 @default.
- W1497751585 cites W2064438027 @default.
- W1497751585 cites W2065264544 @default.
- W1497751585 cites W2065267686 @default.
- W1497751585 cites W2066187005 @default.
- W1497751585 cites W2066710346 @default.
- W1497751585 cites W2067990954 @default.
- W1497751585 cites W2068312225 @default.
- W1497751585 cites W2068919087 @default.
- W1497751585 cites W2069153618 @default.
- W1497751585 cites W2071861150 @default.
- W1497751585 cites W2071920682 @default.
- W1497751585 cites W2072519169 @default.
- W1497751585 cites W2072615138 @default.
- W1497751585 cites W2075464782 @default.
- W1497751585 cites W2080395080 @default.
- W1497751585 cites W2083254579 @default.
- W1497751585 cites W2084223175 @default.
- W1497751585 cites W2086727023 @default.
- W1497751585 cites W2089338061 @default.
- W1497751585 cites W2089849869 @default.
- W1497751585 cites W2090057629 @default.
- W1497751585 cites W2099254609 @default.
- W1497751585 cites W2099481447 @default.
- W1497751585 cites W2106927501 @default.
- W1497751585 cites W2118464638 @default.
- W1497751585 cites W2119408585 @default.