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- W149786072 abstract "The authors wished to determine whether differences in milk intake were solely responsible for differences in the weight gain of rat pups suckled in litters of varying sizes (S = 4, C = 10, L = 16 pups/litter; 9 litters/group). Milk intake was measured (by {sup 3}H{sub 2}O dilution) at 4-6, 8-10, and 14-16 d of age (3 litters of each size/time point). Pup (water, protein, and fat) and milk composition (water, fat, protein and lactose) were analyzed at 6, 10, and 16 d. Dam milk output was positively correlated with litter size and duration of lactation. Milk fat concentration was inversely related to dam milk output (r{sup 2} = 0.79). Weight gain was highest in S litters and lowest in L litters. Weight gain was highly correlated to the volume of milk consumed in S and C pups (r{sup 2} = 81%), but was poorly correlated among L pups (r{sup 2} = 23%). The different correlations may have resulted from (1) the disparate relationship between volume and energy intake of L pups compared to S and C pups, or (2) a higher maintenance energy expenditure in L pups up to 10 d of age determined by a comparison ofmore » the composition of weight gain and energy intake. Thus, the reduced weight gain of pups suckled in large litters resulted from changes in both milk energy intake and the efficiency of its utilization.« less" @default.
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- W149786072 date "1990-02-26" @default.
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- W149786072 title "Litter size influences milk composition and energy expenditure of rat pups" @default.
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