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- W1498341747 abstract "Background and Objective: Human visceral leishmaniasis is endemic in Natal, northeast of Brazil, where the domestic dog is an important parasite reservoir in the infectious cycle of Leishmania spp . In this study, was evaluated the antileishmanial IgG antibody and epidemiological factors related to canine visceral leishmaniasis (CVL). Methods: Sera samples obtained by venipuncture of 1,426 dogs living in areas of human visceral leishmaniasis occurrence were tested for detection of IgG anti- leishmania antibodies with Immunofluorescence Antibody Assay (IFA) and Enzyme Linked Immunosorbent Assay (ELISA). Chi-square (x 2 ) and Odds Ratio (OR) were calculated. Differences were considered statistically significant at p ≤0.05. RESULTS: The overall seroprevalence was 10.30% (147/1,426); prevalence increased when the samples were found to be positive at least for one technique ([417/1,426] 29.3%). The high percentage of seroprevalence was observed in Nova República (15.35%), Nova Natal I (12.7%) and Lagoa Azul (11.4%) neighborhoods. In the Planalto, Soledade and Brasil Novo, the infection rates ranged from 7.5 at 8.06%. ( p =0.00051). There was neither statistically significant difference between leishmanial infection nor clinical signs of disease ( p =0.84; OR=1.0 [0.41; 2.3]), sex ( p =0.78, OR=0.94 [0.66; 1.28]); and breed ( p =0.92; OR=1.0 [0.65; 1.54]) were observed. Conclusion: The RESULTS suggest that CVL is widely distributed in Natal, may be increasingly urbanizing and will spread through neighborhoods but not endemic, resulting in a serious public health problem, emphasizing the need for epidemiological studies to a greater understanding of the distribution of canine leishmaniasis in these specific areas and contribute proactively to the public health policies." @default.
- W1498341747 created "2016-06-24" @default.
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- W1498341747 date "2015-07-31" @default.
- W1498341747 modified "2023-10-16" @default.
- W1498341747 title "Seroepidemiological Survey of Canine Leishmania Infections from Peripheral Areas in Natal, Northeast Brazil" @default.
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- W1498341747 doi "https://doi.org/10.2174/1874285801509010043" @default.
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