Matches in SemOpenAlex for { <https://semopenalex.org/work/W149841323> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W149841323 endingPage "35" @default.
- W149841323 startingPage "429" @default.
- W149841323 abstract "The objective of this study was to describe the development of the secretory immune system (SIS) in the placenta of 32 human fetuses who had died from different causes during the second trimester of pregnancy. The distribution of SIS protein elements, including the secretory component (SC), J-chain, IgA, IgM, IgG, as well subsets of lymphocytes and macrophages, were studied by immunohistochemical methods. Both the fetal and maternal parts of the placenta were found to contain these elements. In the fetal part, the immunoglobulins, SC and J chain were located in the syncytio- and cytotrophoblast of the chorion and in the epithelium of the amnion. The villous stroma contained a small amount of different subsets of lymphocytes. Macrophages accounted for up to 45% of the stromal cells of the villi and contained IgG and J-chain. In the maternal part of the placenta, the SIS proteins were in the decidual cells. Relatively few lymphocytes and macrophages were observed in the decidual stroma. Our data suggest that the placenta has two different SIS, one in the fetal part and the other in the maternal part. They differ in their structure and orientation: the maternal SIS protects the mother against paternal antigens from the fetus, while the fetal SIS protects the fetus against macromolecules and infectious agents penetrating from the mother. The placenta represents the largest extracorporal immune system that is functionally active during the whole second trimester of gestation. We suggest that the concept of placental barrier should be expanded to include both fetal and maternal parts of the SIS, fetal membranes and the decidual tissue." @default.
- W149841323 created "2016-06-24" @default.
- W149841323 creator A5000603242 @default.
- W149841323 creator A5003804287 @default.
- W149841323 creator A5034360312 @default.
- W149841323 creator A5066714669 @default.
- W149841323 creator A5071870224 @default.
- W149841323 creator A5085104836 @default.
- W149841323 date "2001-11-07" @default.
- W149841323 modified "2023-09-23" @default.
- W149841323 title "The secretory immune system as part of the placental barrier in the second trimester of pregnancy in humans." @default.
- W149841323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11695242" @default.
- W149841323 hasPublicationYear "2001" @default.
- W149841323 type Work @default.
- W149841323 sameAs 149841323 @default.
- W149841323 citedByCount "11" @default.
- W149841323 countsByYear W1498413232014 @default.
- W149841323 countsByYear W1498413232015 @default.
- W149841323 countsByYear W1498413232017 @default.
- W149841323 crossrefType "journal-article" @default.
- W149841323 hasAuthorship W149841323A5000603242 @default.
- W149841323 hasAuthorship W149841323A5003804287 @default.
- W149841323 hasAuthorship W149841323A5034360312 @default.
- W149841323 hasAuthorship W149841323A5066714669 @default.
- W149841323 hasAuthorship W149841323A5071870224 @default.
- W149841323 hasAuthorship W149841323A5085104836 @default.
- W149841323 hasConcept C147483822 @default.
- W149841323 hasConcept C159654299 @default.
- W149841323 hasConcept C16685009 @default.
- W149841323 hasConcept C16930146 @default.
- W149841323 hasConcept C172680121 @default.
- W149841323 hasConcept C203014093 @default.
- W149841323 hasConcept C204232928 @default.
- W149841323 hasConcept C2776953305 @default.
- W149841323 hasConcept C2777605040 @default.
- W149841323 hasConcept C2779234561 @default.
- W149841323 hasConcept C2780197806 @default.
- W149841323 hasConcept C2781107390 @default.
- W149841323 hasConcept C502942594 @default.
- W149841323 hasConcept C52124034 @default.
- W149841323 hasConcept C54355233 @default.
- W149841323 hasConcept C71924100 @default.
- W149841323 hasConcept C86803240 @default.
- W149841323 hasConcept C8891405 @default.
- W149841323 hasConcept C97615245 @default.
- W149841323 hasConceptScore W149841323C147483822 @default.
- W149841323 hasConceptScore W149841323C159654299 @default.
- W149841323 hasConceptScore W149841323C16685009 @default.
- W149841323 hasConceptScore W149841323C16930146 @default.
- W149841323 hasConceptScore W149841323C172680121 @default.
- W149841323 hasConceptScore W149841323C203014093 @default.
- W149841323 hasConceptScore W149841323C204232928 @default.
- W149841323 hasConceptScore W149841323C2776953305 @default.
- W149841323 hasConceptScore W149841323C2777605040 @default.
- W149841323 hasConceptScore W149841323C2779234561 @default.
- W149841323 hasConceptScore W149841323C2780197806 @default.
- W149841323 hasConceptScore W149841323C2781107390 @default.
- W149841323 hasConceptScore W149841323C502942594 @default.
- W149841323 hasConceptScore W149841323C52124034 @default.
- W149841323 hasConceptScore W149841323C54355233 @default.
- W149841323 hasConceptScore W149841323C71924100 @default.
- W149841323 hasConceptScore W149841323C86803240 @default.
- W149841323 hasConceptScore W149841323C8891405 @default.
- W149841323 hasConceptScore W149841323C97615245 @default.
- W149841323 hasIssue "5" @default.
- W149841323 hasLocation W1498413231 @default.
- W149841323 hasOpenAccess W149841323 @default.
- W149841323 hasPrimaryLocation W1498413231 @default.
- W149841323 hasRelatedWork W149841323 @default.
- W149841323 hasRelatedWork W2000339122 @default.
- W149841323 hasRelatedWork W2004343427 @default.
- W149841323 hasRelatedWork W2048856649 @default.
- W149841323 hasRelatedWork W2054180428 @default.
- W149841323 hasRelatedWork W2154554478 @default.
- W149841323 hasRelatedWork W2385895345 @default.
- W149841323 hasRelatedWork W2409920057 @default.
- W149841323 hasRelatedWork W2893254440 @default.
- W149841323 hasRelatedWork W4212938483 @default.
- W149841323 hasVolume "15" @default.
- W149841323 isParatext "false" @default.
- W149841323 isRetracted "false" @default.
- W149841323 magId "149841323" @default.
- W149841323 workType "article" @default.