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- W1498623265 abstract "A specific cytotoxic agent against gastric cancer was constructed by covalently coupling the ricin A chain to monoclonal artibody, MGb2. MGb2 was modified by SPDP to introduce the 3-(2-pyridylthio) propionyl radical and then treated with a reduced A chain to give a disulfide linked conjugate that retained the original binding specificity of the antibody moiety. The conjugate obtained retained the activity of the antibody and the biological activity of the A chain well." @default.
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- W1498623265 date "1989-01-01" @default.
- W1498623265 modified "2023-09-23" @default.
- W1498623265 title "SELECTIVE KILLING OF GASTRIC CANCER CELLS BY MONOCLONAL ANTIBODY CONJUGATED WITH A CHAIN OF RICIN" @default.
- W1498623265 hasPublicationYear "1989" @default.
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