Matches in SemOpenAlex for { <https://semopenalex.org/work/W1498981601> ?p ?o ?g. }
- W1498981601 endingPage "375" @default.
- W1498981601 startingPage "371" @default.
- W1498981601 abstract "Palmitate oxidation by liver mitochondria from rats treated with d-galactosamine (GalN) was markedly inhibited, 3 h after administration. 1 The mitochondrial defect responsible for this inhibition was shown to be an inhibition of the activity of palmitoylcarnitine transferase I (EC 2.3.1.21). 2 Apparent Km of the enzyme remained unchanged whereas apparent V was reduced by 30%. 3 Addition of 10 mM GalN did not impair the activity of palmitoylcarnitine transferase I in mitochondria isolated from normal rats. 4 Inhibition of palmitoylcarnitine biosynthesis by GalN treatment was completely reversed by phospholipid supply. 5 At this stage of intoxication, mitochondrial phospholipid content was decreased whereas incorporation of [14C]palmitate into phospholipids in isolated hepatocytes was drastically inhibited; the phosphatidyl-choline/phosphatidylethanolamine ratio was reduced by 33%. The results obtained from these studies show that the depletion of the phospholipid membrane content could account for the altered functional activity of palmitoylcarnitine transferase I." @default.
- W1498981601 created "2016-06-24" @default.
- W1498981601 creator A5014297605 @default.
- W1498981601 creator A5024116939 @default.
- W1498981601 creator A5040255740 @default.
- W1498981601 creator A5053177529 @default.
- W1498981601 creator A5062703759 @default.
- W1498981601 date "1983-11-01" @default.
- W1498981601 modified "2023-10-03" @default.
- W1498981601 title "Carnitine palmitoyltransferase I. Inhibition by d-galactosamine and role of phospholipids" @default.
- W1498981601 cites W14456910 @default.
- W1498981601 cites W1495212988 @default.
- W1498981601 cites W1532333783 @default.
- W1498981601 cites W1544261684 @default.
- W1498981601 cites W1587545793 @default.
- W1498981601 cites W161326241 @default.
- W1498981601 cites W1642077045 @default.
- W1498981601 cites W1775749144 @default.
- W1498981601 cites W1979075614 @default.
- W1498981601 cites W1980387958 @default.
- W1498981601 cites W1986784962 @default.
- W1498981601 cites W1991832287 @default.
- W1498981601 cites W1996780193 @default.
- W1498981601 cites W2011458776 @default.
- W1498981601 cites W2016257988 @default.
- W1498981601 cites W2035470198 @default.
- W1498981601 cites W2059648484 @default.
- W1498981601 cites W2068131934 @default.
- W1498981601 cites W2092861677 @default.
- W1498981601 cites W2115941718 @default.
- W1498981601 cites W2153435210 @default.
- W1498981601 cites W2168526937 @default.
- W1498981601 cites W22160663 @default.
- W1498981601 cites W2252830855 @default.
- W1498981601 cites W2256351467 @default.
- W1498981601 cites W2274254314 @default.
- W1498981601 cites W2318962382 @default.
- W1498981601 cites W2343105053 @default.
- W1498981601 cites W2400019223 @default.
- W1498981601 cites W2432195370 @default.
- W1498981601 cites W342442057 @default.
- W1498981601 doi "https://doi.org/10.1111/j.1432-1033.1983.tb07751.x" @default.
- W1498981601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6628388" @default.
- W1498981601 hasPublicationYear "1983" @default.
- W1498981601 type Work @default.
- W1498981601 sameAs 1498981601 @default.
- W1498981601 citedByCount "32" @default.
- W1498981601 countsByYear W14989816012012 @default.
- W1498981601 countsByYear W14989816012013 @default.
- W1498981601 countsByYear W14989816012014 @default.
- W1498981601 countsByYear W14989816012015 @default.
- W1498981601 countsByYear W14989816012016 @default.
- W1498981601 countsByYear W14989816012020 @default.
- W1498981601 crossrefType "journal-article" @default.
- W1498981601 hasAuthorship W1498981601A5014297605 @default.
- W1498981601 hasAuthorship W1498981601A5024116939 @default.
- W1498981601 hasAuthorship W1498981601A5040255740 @default.
- W1498981601 hasAuthorship W1498981601A5053177529 @default.
- W1498981601 hasAuthorship W1498981601A5062703759 @default.
- W1498981601 hasBestOaLocation W14989816011 @default.
- W1498981601 hasConcept C181199279 @default.
- W1498981601 hasConcept C185592680 @default.
- W1498981601 hasConcept C2776330855 @default.
- W1498981601 hasConcept C2776376580 @default.
- W1498981601 hasConcept C2777615046 @default.
- W1498981601 hasConcept C2778435403 @default.
- W1498981601 hasConcept C2778918659 @default.
- W1498981601 hasConcept C2781170229 @default.
- W1498981601 hasConcept C28212737 @default.
- W1498981601 hasConcept C28859421 @default.
- W1498981601 hasConcept C41625074 @default.
- W1498981601 hasConcept C55493867 @default.
- W1498981601 hasConcept C75385678 @default.
- W1498981601 hasConcept C86803240 @default.
- W1498981601 hasConceptScore W1498981601C181199279 @default.
- W1498981601 hasConceptScore W1498981601C185592680 @default.
- W1498981601 hasConceptScore W1498981601C2776330855 @default.
- W1498981601 hasConceptScore W1498981601C2776376580 @default.
- W1498981601 hasConceptScore W1498981601C2777615046 @default.
- W1498981601 hasConceptScore W1498981601C2778435403 @default.
- W1498981601 hasConceptScore W1498981601C2778918659 @default.
- W1498981601 hasConceptScore W1498981601C2781170229 @default.
- W1498981601 hasConceptScore W1498981601C28212737 @default.
- W1498981601 hasConceptScore W1498981601C28859421 @default.
- W1498981601 hasConceptScore W1498981601C41625074 @default.
- W1498981601 hasConceptScore W1498981601C55493867 @default.
- W1498981601 hasConceptScore W1498981601C75385678 @default.
- W1498981601 hasConceptScore W1498981601C86803240 @default.
- W1498981601 hasIssue "2" @default.
- W1498981601 hasLocation W14989816011 @default.
- W1498981601 hasLocation W14989816012 @default.
- W1498981601 hasOpenAccess W1498981601 @default.
- W1498981601 hasPrimaryLocation W14989816011 @default.
- W1498981601 hasRelatedWork W1498981601 @default.
- W1498981601 hasRelatedWork W1896686934 @default.
- W1498981601 hasRelatedWork W1972665833 @default.
- W1498981601 hasRelatedWork W2050126134 @default.
- W1498981601 hasRelatedWork W2093774542 @default.