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• W1499072828 abstract "Bartonella species have become recognized as substantial human pathogens associated with a wide spectrum of diseases. Four members of the genus are known to cause human infection: Bartonella bacillifarmis, B. henselae, B. quintana, and B. elizabethae. Bacillary peliosis hepatis (BP) is a different vasculoproliferative histopathological entity that occurs in the liver and spleen and occasionally in lymph nodes. Patients with BP can develop thrombocytopenia or pancytopenia and elevated levels of hepatic enzymes, most commonly increased alkaline phosphatase. Bartonella can be isolated directly from the cutaneous lesions of bacillary angiomatosis (BA), but recovery is even more difficult and may require cultivation of biopsied tissue with endothelial cells for weeks. It is likely that cat scratch disease (CSD) is the most commonly recognized Bartonella infection of humans, affecting at least 22,000 people each year and costing more than $12 million annually for diagnosis and treatment in the United States alone. The identification of B. henselae as the agent of CSD and the ability to culture this organism and detect antibodies to it have better defined the spectrum of CSD infection. As with other Bartonella species, the transmission of these four Bartonella species among small mammals is presumed to occur via arthropod vectors. Infection in immunocompromised hosts is associated with an unusual stimulation of vascular proliferation (BA), while infection with the same species, B. hensetae, causes an entirely different histopathological response (CSD) in immunocompetent hosts." @default.
• W1499072828 created "2016-06-24" @default.
• W1499072828 creator A5074353326 @default.
• W1499072828 date "2014-04-09" @default.
• W1499072828 modified "2023-09-25" @default.
• W1499072828 title "Bartonella: an Emerging Human Pathogen" @default.
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• W1499072828 doi "https://doi.org/10.1128/9781555816940.ch10" @default.
• W1499072828 hasPublicationYear "2014" @default.
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