FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1499694722> ?p ?o ?g. }

• W1499694722 endingPage "651" @default.
• W1499694722 startingPage "643" @default.
• W1499694722 abstract "We recently reported, in a prospective randomized trial, that ultra-staging of patients with colon cancer is associated with significantly improved disease-free survival (DFS) compared with conventional staging. That trial did not control for lymph node (LN) number or adjuvant chemotherapy use.The current international prospective multicenter cooperative group trial (ClinicalTrials.gov identifier NCT00949312; Ultra-staging in Early Colon Cancer) evaluates the 12-LN quality measure and nodal ultra-staging impact on DFS in patients not receiving adjuvant chemotherapy. Eligibility criteria included biopsy-proven colon adenocarcinoma; absence of metastatic disease; >12 LNs staged pathologically; pan-cytokeratin immunohistochemistry (IHC) of hematoxylin and eosin (H&E)-negative LNs; and no adjuvant chemotherapy.Of 445 patients screened, 203 patients were eligible. The majority of patients had intermediate grade (57.7%) and T3 tumors (64.9%). At a mean follow-up of 36.8 ± 22.1 months (range 0 to 97 months), 94.3% remain disease free. Recurrence was least likely in patients with ≥12 LNs, H&E-negative LNs, and IHC-negative LNs (pN0i-): 2.6% vs 16.7% in the pN0i+ group (p < 0.0001).This is the first prospective report to demonstrate that patients with optimally staged node-negative colon cancer (≥12 LNs, pN0i-) are unlikely to benefit from adjuvant chemotherapy; 97% remain disease free after primary tumor resection. Both surgical and pathologic quality measures are imperative in planning clinical trials in nonmetastatic colon cancer." @default.
• W1499694722 created "2016-06-24" @default.
• W1499694722 creator A5008106546 @default.
• W1499694722 creator A5019473289 @default.
• W1499694722 creator A5021850293 @default.
• W1499694722 creator A5023731138 @default.
• W1499694722 creator A5048474812 @default.
• W1499694722 creator A5077660936 @default.
• W1499694722 creator A5080661758 @default.
• W1499694722 creator A5086555890 @default.
• W1499694722 date "2015-09-01" @default.
• W1499694722 modified "2023-10-16" @default.
• W1499694722 title "Prognostic Effect of Ultra-Staging Node-Negative Colon Cancer Without Adjuvant Chemotherapy: A Prospective National Cancer Institute-Sponsored Clinical Trial" @default.
• W1499694722 cites W1527749181 @default.
• W1499694722 cites W17456534 @default.
• W1499694722 cites W1839179899 @default.
• W1499694722 cites W1844854109 @default.
• W1499694722 cites W1965615067 @default.
• W1499694722 cites W1967033597 @default.
• W1499694722 cites W1971046017 @default.
• W1499694722 cites W1973402430 @default.
• W1499694722 cites W1976067359 @default.
• W1499694722 cites W1980824358 @default.
• W1499694722 cites W1982888061 @default.
• W1499694722 cites W1983337227 @default.
• W1499694722 cites W1990545152 @default.
• W1499694722 cites W1993965603 @default.
• W1499694722 cites W2007844116 @default.
• W1499694722 cites W2012181990 @default.
• W1499694722 cites W203485574 @default.
• W1499694722 cites W2042926770 @default.
• W1499694722 cites W2044608166 @default.
• W1499694722 cites W2048242236 @default.
• W1499694722 cites W2049103906 @default.
• W1499694722 cites W2066000681 @default.
• W1499694722 cites W2086851328 @default.
• W1499694722 cites W2089300758 @default.
• W1499694722 cites W2106787323 @default.
• W1499694722 cites W2108509187 @default.
• W1499694722 cites W2109740395 @default.
• W1499694722 cites W2121294912 @default.
• W1499694722 cites W2121327919 @default.
• W1499694722 cites W2135357582 @default.
• W1499694722 cites W2140340422 @default.
• W1499694722 cites W2144495943 @default.
• W1499694722 cites W2154821765 @default.
• W1499694722 cites W2162102504 @default.
• W1499694722 cites W2165643303 @default.
• W1499694722 cites W2169458356 @default.
• W1499694722 cites W2170552969 @default.
• W1499694722 cites W2219571586 @default.
• W1499694722 cites W2323930585 @default.
• W1499694722 cites W2339671919 @default.
• W1499694722 cites W2917837889 @default.
• W1499694722 cites W4255935766 @default.
• W1499694722 doi "https://doi.org/10.1016/j.jamcollsurg.2015.05.007" @default.
• W1499694722 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4657939" @default.
• W1499694722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26213360" @default.
• W1499694722 hasPublicationYear "2015" @default.
• W1499694722 type Work @default.
• W1499694722 sameAs 1499694722 @default.
• W1499694722 citedByCount "21" @default.
• W1499694722 countsByYear W14996947222015 @default.
• W1499694722 countsByYear W14996947222016 @default.
• W1499694722 countsByYear W14996947222017 @default.
• W1499694722 countsByYear W14996947222018 @default.
• W1499694722 countsByYear W14996947222019 @default.
• W1499694722 countsByYear W14996947222020 @default.
• W1499694722 countsByYear W14996947222021 @default.
• W1499694722 countsByYear W14996947222022 @default.
• W1499694722 crossrefType "journal-article" @default.
• W1499694722 hasAuthorship W1499694722A5008106546 @default.
• W1499694722 hasAuthorship W1499694722A5019473289 @default.
• W1499694722 hasAuthorship W1499694722A5021850293 @default.
• W1499694722 hasAuthorship W1499694722A5023731138 @default.
• W1499694722 hasAuthorship W1499694722A5048474812 @default.
• W1499694722 hasAuthorship W1499694722A5077660936 @default.
• W1499694722 hasAuthorship W1499694722A5080661758 @default.
• W1499694722 hasAuthorship W1499694722A5086555890 @default.
• W1499694722 hasBestOaLocation W14996947222 @default.
• W1499694722 hasConcept C121608353 @default.
• W1499694722 hasConcept C126322002 @default.
• W1499694722 hasConcept C141071460 @default.
• W1499694722 hasConcept C143998085 @default.
• W1499694722 hasConcept C188816634 @default.
• W1499694722 hasConcept C2776694085 @default.
• W1499694722 hasConcept C2778260052 @default.
• W1499694722 hasConcept C2780849966 @default.
• W1499694722 hasConcept C2780962732 @default.
• W1499694722 hasConcept C526805850 @default.
• W1499694722 hasConcept C71924100 @default.
• W1499694722 hasConceptScore W1499694722C121608353 @default.
• W1499694722 hasConceptScore W1499694722C126322002 @default.
• W1499694722 hasConceptScore W1499694722C141071460 @default.
• W1499694722 hasConceptScore W1499694722C143998085 @default.
• W1499694722 hasConceptScore W1499694722C188816634 @default.
• W1499694722 hasConceptScore W1499694722C2776694085 @default.
• W1499694722 hasConceptScore W1499694722C2778260052 @default.

• next