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• W1499932004 startingPage "440" @default.
• W1499932004 abstract "Reactive oxygen species (ROS) such as the superoxide anion radical (O2.-) hydrogen peroxide (H2O2) and hydroxyl radical (.OH) have been implicated in the pathophysiology of various states, including ischemia reperfusion injury, haemorrhagic shock, atherosclerosis, heart failure, acute hypertension and cancer. The free radicals, nitric oxide (NO) and O2.- react to form peroxynitrite (ONOO-), a potent cytotoxic oxidant. A potential mechanism of oxidative damage is the nitration of tyrosine residues of protein, peroxidation of lipids, degradation of DNA and oligonucleosomal fragments. Several mechanisms are responsible for the protection of the cells from potential cytotoxic damage caused by free radicals. Cells have developed various enzymatic and nonenzymatic defense systems to control excited oxygen species, however, a certain fraction escapes the cellular defense and may cause permanent or transient damage to nucleic acids within the cells, leading to such events as DNA strand breakage and disruption of Ca2+ metabolism. There is currently great interest in the possible role of ROS in causing DNA damage that leads to cancer and spontaneous mutations. A high rate of oxidative damage to mammalian DNA has been demonstrated by measuring oxidized DNA bases excreted in urine after DNA repair. The rate of oxidative DNA damage is directly related to the metabolic rate and inversely related to life span of the organism." @default.
• W1499932004 created "2016-06-24" @default.
• W1499932004 creator A5002895682 @default.
• W1499932004 creator A5025475085 @default.
• W1499932004 date "1998-10-01" @default.
• W1499932004 modified "2023-10-01" @default.
• W1499932004 title "Reactive oxygen species and oxidative DNA damage." @default.
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• W1499932004 cites W1498983801 @default.
• W1499932004 cites W1535816350 @default.
• W1499932004 cites W1539297835 @default.
• W1499932004 cites W1847864430 @default.
• W1499932004 cites W1853607111 @default.
• W1499932004 cites W1952402412 @default.
• W1499932004 cites W1966799916 @default.
• W1499932004 cites W1971748722 @default.
• W1499932004 cites W1979092465 @default.
• W1499932004 cites W1981510143 @default.
• W1499932004 cites W1982518099 @default.
• W1499932004 cites W1982605253 @default.
• W1499932004 cites W1984119574 @default.
• W1499932004 cites W1984373476 @default.
• W1499932004 cites W1991261610 @default.
• W1499932004 cites W1999368137 @default.
• W1499932004 cites W1999649376 @default.
• W1499932004 cites W2003471941 @default.
• W1499932004 cites W2004276705 @default.
• W1499932004 cites W2005502331 @default.
• W1499932004 cites W2005629029 @default.
• W1499932004 cites W2005840034 @default.
• W1499932004 cites W2006294958 @default.
• W1499932004 cites W2010094123 @default.
• W1499932004 cites W2012123962 @default.
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• W1499932004 cites W2016658034 @default.
• W1499932004 cites W2027403336 @default.
• W1499932004 cites W2027677864 @default.
• W1499932004 cites W2027925323 @default.
• W1499932004 cites W2029054651 @default.
• W1499932004 cites W2030061265 @default.
• W1499932004 cites W2030283142 @default.
• W1499932004 cites W2031412848 @default.
• W1499932004 cites W2031532246 @default.
• W1499932004 cites W2031619229 @default.
• W1499932004 cites W2032568967 @default.
• W1499932004 cites W2036690044 @default.
• W1499932004 cites W2037217405 @default.
• W1499932004 cites W2042369211 @default.
• W1499932004 cites W2046422488 @default.
• W1499932004 cites W2049775789 @default.
• W1499932004 cites W2059364017 @default.
• W1499932004 cites W2063976102 @default.
• W1499932004 cites W2065700794 @default.
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• W1499932004 cites W2075479169 @default.
• W1499932004 cites W2081745487 @default.
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• W1499932004 cites W2142441082 @default.
• W1499932004 cites W2164613158 @default.
• W1499932004 cites W2177214907 @default.
• W1499932004 cites W2254390186 @default.
• W1499932004 cites W2338707059 @default.
• W1499932004 cites W2340686756 @default.
• W1499932004 cites W2412928376 @default.
• W1499932004 cites W2414123687 @default.
• W1499932004 cites W28619635 @default.
• W1499932004 cites W408505 @default.
• W1499932004 cites W4454459 @default.
• W1499932004 cites W56030629 @default.
• W1499932004 cites W625127082 @default.
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• W1499932004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10874342" @default.
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