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- W150052986 abstract "duced to defi ne the application of spectrophotometry in the visible/near infrared region to the understanding of the infl uence of water on the structure and functioning of biological systems. Nowadays, medical and veterinary di- agnostics is supported by clinical chem- istry and near infrared (NIR) spectroscopy is adding a new dimension with very high potential to provide valuable information in this area. Recent work on mastitis diagnos- tics with NIR spectroscopy has shown that the spectra of biofl uids, such as raw milk, blood, urine and rumen juice, are very simi- lar. 2 This result is logical because all of these sample types are dominated by water and water strongly absorbs NIR light energy. Further study showed that the loadings and regression vectors developed for various constituents in these fl uids had a substan- tial number of common wavelengths of high importance to each respective model. The intriguing fi nding was that some of these common wavelengths were well-known water absorbance bands, no matter what was the measured substance. Further on, spectra of the biological fl u- ids referred to above were re-examined to determine how this new WAMACS con- cept could be used in the interpretation of biological phenomena. Water is a natural biological matrix containing only small mol- ecules and hydrogen bonding, and chang- es its absorbance pattern when adapting to physical or chemical change in biologi- cal systems. It was considered that water activating perturbations (WAPs) could be an effective way to increase the information for the solute extracted from the spectra, to obtain new knowledge related to func- tionality of water in biological systems and for diagnosis. Using WAPs, the spectral gradient at a number of wavelengths ob- tained under various perturbations allowed measurement of even subtle quantities or structural changes of other molecules in the system. 9" @default.
- W150052986 created "2016-06-24" @default.
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- W150052986 date "2007-03-01" @default.
- W150052986 modified "2023-09-27" @default.
- W150052986 title "AquaPhotomics: Water Absorbance Pattern as a Biological Marker for Disease Diagnosis and Disease Understanding" @default.
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- W150052986 doi "https://doi.org/10.1255/nirn.1014" @default.
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