FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W150060329> ?p ?o ?g. }

• W150060329 endingPage "282" @default.
• W150060329 startingPage "269" @default.
• W150060329 abstract "Maturation of mammalian oocytes is studied mainly in two dissimilar in vitro models: isolated oocytes maturing spontaneously in culture, and hormone-induced maturation of follicle-enclosed oocytes. In this discussion the following aspects of maturation in vitro in the two aforementioned models were compared: timing of germinal vesicle breakdown (GVB), involvement of cyclic nucleotides, protein synthesis and divalent cations. A third approach to the study of oocyte maturation in vitro, namely oocyte co-culture with follicular constituents was adopted in order to test the role of follicular components in the control of the resumption of meiosis. Such studies demonstrated an inhibitory action of granulosa cells, granulosa cell-conditioned medium and of follicular fluid upon the spontaneous maturation of the co-cultured oocytes. Furthermore, addition of LH to co-cultures of oocytes and granulosa cells induced resumption of meiosis. Although oocytes obtained by spontaneous or by hormone-induced maturation cannot be distinguished morphologically, the developmental potential of oocytes matured spontaneously has been questioned, at least in some species. Furthermore, analysis of the kinetics of spontaneous maturation suggests that oocytes dislodged from their follicles escape physiologic mechanisms ensuring meiotic arrest and skip some of the regulatory steps involved in the normal hormonal triggering of maturation. Oocyte co-culture with granulosa cells offers a close approximation to physiological conditions in that meiotic maturation depends on hormonal stimulation, while the system permits the application of separate treatments to the oocyte-cumulus complex and granulosa cells. As in any in vitro system, critical evaluation is required to discriminate between artifacts inherent in the model and physiological processes." @default.
• W150060329 created "2016-06-24" @default.
• W150060329 creator A5052042296 @default.
• W150060329 date "1979-01-01" @default.
• W150060329 modified "2023-10-14" @default.
• W150060329 title "Mammalian Oocyte Maturation: Model Systems and Their Physiological Relevance" @default.
• W150060329 cites W1932794209 @default.
• W150060329 cites W1968168871 @default.
• W150060329 cites W1971506156 @default.
• W150060329 cites W1972235343 @default.
• W150060329 cites W1976580430 @default.
• W150060329 cites W1981794598 @default.
• W150060329 cites W1984305127 @default.
• W150060329 cites W1986140299 @default.
• W150060329 cites W1988188906 @default.
• W150060329 cites W1988544416 @default.
• W150060329 cites W2010184839 @default.
• W150060329 cites W2018783350 @default.
• W150060329 cites W2019097335 @default.
• W150060329 cites W2024364788 @default.
• W150060329 cites W2039595930 @default.
• W150060329 cites W2062415723 @default.
• W150060329 cites W2073719216 @default.
• W150060329 cites W2078727052 @default.
• W150060329 cites W2081487791 @default.
• W150060329 cites W2103750154 @default.
• W150060329 cites W2131338581 @default.
• W150060329 cites W2131553631 @default.
• W150060329 cites W2145134793 @default.
• W150060329 cites W2150083639 @default.
• W150060329 cites W2181917632 @default.
• W150060329 cites W2295074165 @default.
• W150060329 cites W2334708595 @default.
• W150060329 cites W2409840287 @default.
• W150060329 cites W2410961661 @default.
• W150060329 doi "https://doi.org/10.1007/978-1-4684-3474-3_32" @default.
• W150060329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/223389" @default.
• W150060329 hasPublicationYear "1979" @default.
• W150060329 type Work @default.
• W150060329 sameAs 150060329 @default.
• W150060329 citedByCount "26" @default.
• W150060329 countsByYear W1500603292012 @default.
• W150060329 countsByYear W1500603292013 @default.
• W150060329 countsByYear W1500603292015 @default.
• W150060329 countsByYear W1500603292016 @default.
• W150060329 countsByYear W1500603292020 @default.
• W150060329 countsByYear W1500603292023 @default.
• W150060329 crossrefType "book-chapter" @default.
• W150060329 hasAuthorship W150060329A5052042296 @default.
• W150060329 hasConcept C104317684 @default.
• W150060329 hasConcept C126322002 @default.
• W150060329 hasConcept C134018914 @default.
• W150060329 hasConcept C148196450 @default.
• W150060329 hasConcept C16685009 @default.
• W150060329 hasConcept C185592680 @default.
• W150060329 hasConcept C187785154 @default.
• W150060329 hasConcept C196843134 @default.
• W150060329 hasConcept C202751555 @default.
• W150060329 hasConcept C2775966511 @default.
• W150060329 hasConcept C2776188440 @default.
• W150060329 hasConcept C2776690073 @default.
• W150060329 hasConcept C2994119143 @default.
• W150060329 hasConcept C54355233 @default.
• W150060329 hasConcept C71315377 @default.
• W150060329 hasConcept C71924100 @default.
• W150060329 hasConcept C86803240 @default.
• W150060329 hasConcept C95444343 @default.
• W150060329 hasConceptScore W150060329C104317684 @default.
• W150060329 hasConceptScore W150060329C126322002 @default.
• W150060329 hasConceptScore W150060329C134018914 @default.
• W150060329 hasConceptScore W150060329C148196450 @default.
• W150060329 hasConceptScore W150060329C16685009 @default.
• W150060329 hasConceptScore W150060329C185592680 @default.
• W150060329 hasConceptScore W150060329C187785154 @default.
• W150060329 hasConceptScore W150060329C196843134 @default.
• W150060329 hasConceptScore W150060329C202751555 @default.
• W150060329 hasConceptScore W150060329C2775966511 @default.
• W150060329 hasConceptScore W150060329C2776188440 @default.
• W150060329 hasConceptScore W150060329C2776690073 @default.
• W150060329 hasConceptScore W150060329C2994119143 @default.
• W150060329 hasConceptScore W150060329C54355233 @default.
• W150060329 hasConceptScore W150060329C71315377 @default.
• W150060329 hasConceptScore W150060329C71924100 @default.
• W150060329 hasConceptScore W150060329C86803240 @default.
• W150060329 hasConceptScore W150060329C95444343 @default.
• W150060329 hasLocation W1500603291 @default.
• W150060329 hasLocation W1500603292 @default.
• W150060329 hasOpenAccess W150060329 @default.
• W150060329 hasPrimaryLocation W1500603291 @default.
• W150060329 hasRelatedWork W1531690305 @default.
• W150060329 hasRelatedWork W2078114302 @default.
• W150060329 hasRelatedWork W2085490784 @default.
• W150060329 hasRelatedWork W2087413451 @default.
• W150060329 hasRelatedWork W2096840649 @default.
• W150060329 hasRelatedWork W2298618936 @default.
• W150060329 hasRelatedWork W2374597597 @default.
• W150060329 hasRelatedWork W2383669106 @default.
• W150060329 hasRelatedWork W2386382534 @default.

• next