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- W1500683491 abstract "Background: The severity of airflow limitation and the presence of exacerbations are two of the main aspects that contribute to the burden of chronic obstructive pulmonary disease (COPD). Aim: To evaluate the presence of moderate and severe exacerbations in COPD patients and its relation with the severity of airway limitation. Methods: 147 consecutive patients from the outpatient clinic of our Pneumology Department were stratified according to the spirometric staging proposed by GOLD guidelines. The clinical records of the patients were reviewed and data regarding to their exacerbation history were collected. We defined as exclusion criteria: age ≥ 80 years, FEV1 ≥ 80% predicted, and history of lung cancer or congestive heart failure. We considered as severe exacerbations those that required hospital admission. The Chi-square test was used for the statistical analysis; statistical significance was admitted for values of p Results: 100 patients were included. The mean age was 66 years (±8), 83% were male and 70% were former smokers. There was statistical significance for the results presented below (p-value From the 34 patients with ≥ 2 exacerbations in the last year, 71% had ≥ 2 exacerbations in the previous year. Conclusions: As shown in other studies, worsening airflow limitation is associated with an increasing prevalence of exacerbations. We emphasize that in the GOLD 4 group 48% of patients had at least 3 events in a year and 57% had at least one hospitalization consequent to COPD. On the other hand, in the GOLD 2 group 60% had no exacerbations and no patient had 3 exacerbations." @default.
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- W1500683491 date "2013-09-01" @default.
- W1500683491 modified "2023-09-25" @default.
- W1500683491 title "Frequency of COPD exacerbations and severity of COPD" @default.
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