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• W1500935658 endingPage "169" @default.
• W1500935658 startingPage "156" @default.
• W1500935658 abstract "JRAAS 2001;2:156-69 Introduction Primary aldosteronism (PAL) is characterised by aldosterone production which is excessive to the body’s requirements and relatively autonomous of its normal chronic regulator, angiotensin II (Ang II). Inappropriate aldosterone production results in excessive reabsorption of sodium via the amiloride-sensitive epithelial sodium channels situated within the distal tubule and collecting duct of the kidney (leading to hypertension), and continues in the face of suppression of the reninangiotensin system (RAS). Urinary loss of potassium, which is exchanged for sodium at the distal nephron, may eventually result in hypokalaemia if severe and prolonged enough. Because measurements of plasma aldosterone and plasma renin activity (PRA) have become readily available, it is now feasible to measure their relationship in all hypertensive patients. The wide application of the aldosterone/PRA ratio (ARR) has permitted the diagnosis of PAL in the absence of hypokalaemia,and more commonly, in fact, than in the presence of hypokalaemia. This has led to a new understanding that PAL is not a rare cause of hypertension, to be suspected only when hypokalaemia is present, but is probably the commonest, identifiable, specifically treatable and potentially curable form of hypertension. With most recent studies reporting prevalence rates for PAL that are much higher than those previously described in medical textbooks and reviews on the subject, the diagnosis of PAL is likely to become an increasingly frequent event. The ability to correctly apply diagnostic techniques involved in the workup of PAL and to interpret their results therefore represent skills of increasing importance for physicians who treat hypertension. This review focuses on the rationale and methodology of these diagnostic techniques, and on current approaches to management of patients with PAL." @default.
• W1500935658 created "2016-06-24" @default.
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• W1500935658 creator A5088753364 @default.
• W1500935658 date "2001-09-01" @default.
• W1500935658 modified "2023-09-26" @default.
• W1500935658 title "Review: Diagnosis and management of primary aldosteronism" @default.
• W1500935658 cites W1537737553 @default.
• W1500935658 cites W1566388534 @default.
• W1500935658 cites W1968024906 @default.
• W1500935658 cites W1972651891 @default.
• W1500935658 cites W1977013284 @default.
• W1500935658 cites W1977014222 @default.
• W1500935658 cites W1977152294 @default.
• W1500935658 cites W1977415769 @default.
• W1500935658 cites W1979069430 @default.
• W1500935658 cites W1980312558 @default.
• W1500935658 cites W1984388924 @default.
• W1500935658 cites W1987160951 @default.
• W1500935658 cites W1987354827 @default.
• W1500935658 cites W1987819989 @default.
• W1500935658 cites W1990808750 @default.
• W1500935658 cites W1991955496 @default.
• W1500935658 cites W1993792306 @default.
• W1500935658 cites W1995526554 @default.
• W1500935658 cites W1996245314 @default.
• W1500935658 cites W1997388963 @default.
• W1500935658 cites W2001053537 @default.
• W1500935658 cites W2003250762 @default.
• W1500935658 cites W2004886756 @default.
• W1500935658 cites W2008783462 @default.
• W1500935658 cites W2010695765 @default.
• W1500935658 cites W2015622803 @default.
• W1500935658 cites W2018181277 @default.
• W1500935658 cites W2022880162 @default.
• W1500935658 cites W2024256442 @default.
• W1500935658 cites W2025167826 @default.
• W1500935658 cites W2025359340 @default.
• W1500935658 cites W2030789705 @default.
• W1500935658 cites W2034198664 @default.
• W1500935658 cites W2036247250 @default.
• W1500935658 cites W2038466626 @default.
• W1500935658 cites W2039397242 @default.
• W1500935658 cites W2052724934 @default.
• W1500935658 cites W2054019359 @default.
• W1500935658 cites W2059423103 @default.
• W1500935658 cites W2060227248 @default.
• W1500935658 cites W2062442306 @default.
• W1500935658 cites W2062905146 @default.
• W1500935658 cites W2063599459 @default.
• W1500935658 cites W2064320461 @default.
• W1500935658 cites W2065949740 @default.
• W1500935658 cites W2068656310 @default.
• W1500935658 cites W2070112849 @default.
• W1500935658 cites W2071349138 @default.
• W1500935658 cites W2071801871 @default.
• W1500935658 cites W2073219251 @default.
• W1500935658 cites W2075319725 @default.
• W1500935658 cites W2075460104 @default.
• W1500935658 cites W2077000998 @default.
• W1500935658 cites W2079620052 @default.
• W1500935658 cites W2082104489 @default.
• W1500935658 cites W2088069923 @default.
• W1500935658 cites W2089285531 @default.
• W1500935658 cites W2095260125 @default.
• W1500935658 cites W2106441560 @default.
• W1500935658 cites W2108405883 @default.
• W1500935658 cites W2140853270 @default.
• W1500935658 cites W2142766228 @default.
• W1500935658 cites W2154966863 @default.
• W1500935658 cites W2156261944 @default.
• W1500935658 cites W2160494459 @default.
• W1500935658 cites W2313280149 @default.
• W1500935658 cites W2323458614 @default.
• W1500935658 cites W2342067247 @default.
• W1500935658 cites W2399178911 @default.
• W1500935658 cites W2557454322 @default.
• W1500935658 cites W4231249271 @default.
• W1500935658 cites W4235000915 @default.
• W1500935658 cites W4236671013 @default.
• W1500935658 cites W4241786233 @default.
• W1500935658 cites W4244415926 @default.
• W1500935658 cites W4246087126 @default.
• W1500935658 cites W4253054006 @default.
• W1500935658 cites W4296153575 @default.
• W1500935658 cites W4317523829 @default.
• W1500935658 cites W4327849069 @default.
• W1500935658 doi "https://doi.org/10.3317/jraas.2001.022" @default.
• W1500935658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11881117" @default.
• W1500935658 hasPublicationYear "2001" @default.
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