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- W1500955360 abstract "Abstract Soluble tetanus toxoid given as an aerosol to human volunteers led to an increase in serum antibody titers comparable to that resulting from conventional subcutaneous administration, thus suggesting that tetanus toxoid booster immunization can be administered by aerosol in man. The results also show that an antigen given by fine particle aerosol can stimulate the production of high levels of serum antibody. No increase in the titer of nasal antibody was demonstrated. Sputum antibody titers, however, were found to increase significantly in the persons who received aerosolized vaccine, which demonstrates that secretory antibody was produced in response to an antigen that normally does not enter the respiratory tract." @default.
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- W1500955360 date "1969-11-01" @default.
- W1500955360 modified "2023-09-26" @default.
- W1500955360 title "Aerosol Immunization of Humans with Tetanus Toxoid" @default.
- W1500955360 doi "https://doi.org/10.4049/jimmunol.103.5.1096" @default.
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