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- W1501470177 abstract "organism. Blood cell production is sustained throughout the life of an organism by a population of self-renewing multipotent hematopoietic stem cells (HSCs). There are three hallmark characteristics of the HSCs: ability for self-renew, potential to differentiate into all hematopoietic lineages, and capacity for long-term reconstitution (LTR) of the hematopoietic system when transplanted into lethally irradiated recipients. Vertebrate hematopoiesis is thought to occur in two successive waves, primitive and definitive, which differ in the cell types produced and their anatomic location. Whereas the primitive wave occurs transiently and produces only certain blood lineages, the definitive program continues throughout the whole lifespan and produces HSCs capable of giving rise to all blood lineages (rev. in Galloway et al., 2003)." @default.
- W1501470177 created "2016-06-24" @default.
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- W1501470177 date "2010-01-01" @default.
- W1501470177 modified "2023-09-27" @default.
- W1501470177 title "Role of the homeobox gene Meis 1 in hematopoietic stem cells generation in the vertebrate embryo: a functional analysis" @default.
- W1501470177 hasPublicationYear "2010" @default.
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