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- W1501471226 abstract "Abstract The kinetics for inactivation of rat liver membrane adenylate cyclase by iodoacetamide is reported. Glucagon at 1 µm stimulates the rate of inactivation by a factor of 10-fold. It is proposed that interaction of glucagon with its receptor in the membranes promotes conformational changes which either increase exposure or enhance nucleophilicity of one or more sulfhydryl groups crucial for adenylate cyclase activity. The possibility that hormonal stimulation of adenylate cyclase may be mediated through sulfhydryl reactivity is considered." @default.
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- W1501471226 date "1973-07-01" @default.
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- W1501471226 title "Glucagon Stimulation of Adenylate Cyclase Sulfhydryl Reactivity" @default.
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- W1501471226 doi "https://doi.org/10.1016/s0021-9258(19)43691-0" @default.
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