Matches in SemOpenAlex for { <https://semopenalex.org/work/W1501887912> ?p ?o ?g. }
- W1501887912 endingPage "260" @default.
- W1501887912 startingPage "253" @default.
- W1501887912 abstract "Abstract Objectives We have previously found that volume-regulated chloride current (VRCC) is involved in cell cycle progression and cell proliferation. This study was to examine the effect of Tween 80, a nonionic surfactant, on VRCC and cell proliferation in rat basilar artery smooth muscle cells (BASMCs). Methods VRCC was recorded using a whole-cell patch clamp. Cell proliferation and cell cycle were determined by CCK-8, cell count and flow cytometry. Key findings The results showed that endothelin-1 promotes cell cycle transition from the G0/G1 phase to the S phase and significantly increases VRCC in BASMCs. The effect of Tween 80 on VRCC is reversible and concentration dependent. However, this chemical has no effect on the calcium-activated chloride channel. Tween 80 also concentration-dependently inhibits BASMCs proliferation and arrests cells in the G1/S checkpoint. The antiproliferative effect is paralleled with the inhibitory effect on VRCC. Conclutision Our study demonstrates that the inhibitory effect of Tween 80 on VRCC contributes importantly to arrest of the cell cycle and prevention of cell proliferation." @default.
- W1501887912 created "2016-06-24" @default.
- W1501887912 creator A5009087892 @default.
- W1501887912 creator A5041942709 @default.
- W1501887912 creator A5049638902 @default.
- W1501887912 creator A5061437968 @default.
- W1501887912 date "2011-01-14" @default.
- W1501887912 modified "2023-10-18" @default.
- W1501887912 title "Effects of Tween 80 on volume-regulated chloride channel and cell proliferation in rat basilar artery smooth muscle cell" @default.
- W1501887912 cites W1498851698 @default.
- W1501887912 cites W1966960575 @default.
- W1501887912 cites W1967129717 @default.
- W1501887912 cites W1970266437 @default.
- W1501887912 cites W1971096774 @default.
- W1501887912 cites W1983743709 @default.
- W1501887912 cites W2000492865 @default.
- W1501887912 cites W2010281502 @default.
- W1501887912 cites W2012607597 @default.
- W1501887912 cites W2017720960 @default.
- W1501887912 cites W2018729486 @default.
- W1501887912 cites W2020820462 @default.
- W1501887912 cites W2023751546 @default.
- W1501887912 cites W2025797843 @default.
- W1501887912 cites W2035320088 @default.
- W1501887912 cites W2039403859 @default.
- W1501887912 cites W2044050922 @default.
- W1501887912 cites W2046728004 @default.
- W1501887912 cites W2047936759 @default.
- W1501887912 cites W2049130672 @default.
- W1501887912 cites W2050753670 @default.
- W1501887912 cites W2057564536 @default.
- W1501887912 cites W2058083125 @default.
- W1501887912 cites W2061939104 @default.
- W1501887912 cites W2068060366 @default.
- W1501887912 cites W2068505752 @default.
- W1501887912 cites W2070424505 @default.
- W1501887912 cites W2072398283 @default.
- W1501887912 cites W2088197671 @default.
- W1501887912 cites W2091051557 @default.
- W1501887912 cites W2109075580 @default.
- W1501887912 cites W2116333291 @default.
- W1501887912 cites W2134999414 @default.
- W1501887912 cites W2147682631 @default.
- W1501887912 cites W2159974610 @default.
- W1501887912 cites W2169480140 @default.
- W1501887912 cites W2322857662 @default.
- W1501887912 doi "https://doi.org/10.1111/j.2042-7158.2010.01209.x" @default.
- W1501887912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21235590" @default.
- W1501887912 hasPublicationYear "2011" @default.
- W1501887912 type Work @default.
- W1501887912 sameAs 1501887912 @default.
- W1501887912 citedByCount "5" @default.
- W1501887912 countsByYear W15018879122012 @default.
- W1501887912 countsByYear W15018879122014 @default.
- W1501887912 countsByYear W15018879122015 @default.
- W1501887912 countsByYear W15018879122022 @default.
- W1501887912 crossrefType "journal-article" @default.
- W1501887912 hasAuthorship W1501887912A5009087892 @default.
- W1501887912 hasAuthorship W1501887912A5041942709 @default.
- W1501887912 hasAuthorship W1501887912A5049638902 @default.
- W1501887912 hasAuthorship W1501887912A5061437968 @default.
- W1501887912 hasBestOaLocation W15018879121 @default.
- W1501887912 hasConcept C1491633281 @default.
- W1501887912 hasConcept C153911025 @default.
- W1501887912 hasConcept C185592680 @default.
- W1501887912 hasConcept C29537977 @default.
- W1501887912 hasConcept C553184892 @default.
- W1501887912 hasConcept C55493867 @default.
- W1501887912 hasConcept C62112901 @default.
- W1501887912 hasConcept C86803240 @default.
- W1501887912 hasConcept C95444343 @default.
- W1501887912 hasConceptScore W1501887912C1491633281 @default.
- W1501887912 hasConceptScore W1501887912C153911025 @default.
- W1501887912 hasConceptScore W1501887912C185592680 @default.
- W1501887912 hasConceptScore W1501887912C29537977 @default.
- W1501887912 hasConceptScore W1501887912C553184892 @default.
- W1501887912 hasConceptScore W1501887912C55493867 @default.
- W1501887912 hasConceptScore W1501887912C62112901 @default.
- W1501887912 hasConceptScore W1501887912C86803240 @default.
- W1501887912 hasConceptScore W1501887912C95444343 @default.
- W1501887912 hasIssue "2" @default.
- W1501887912 hasLocation W15018879121 @default.
- W1501887912 hasLocation W15018879122 @default.
- W1501887912 hasOpenAccess W1501887912 @default.
- W1501887912 hasPrimaryLocation W15018879121 @default.
- W1501887912 hasRelatedWork W1686076540 @default.
- W1501887912 hasRelatedWork W2350294409 @default.
- W1501887912 hasRelatedWork W2351474733 @default.
- W1501887912 hasRelatedWork W2363671651 @default.
- W1501887912 hasRelatedWork W2373562757 @default.
- W1501887912 hasRelatedWork W2374592133 @default.
- W1501887912 hasRelatedWork W2379910594 @default.
- W1501887912 hasRelatedWork W2387175565 @default.
- W1501887912 hasRelatedWork W2387753559 @default.
- W1501887912 hasRelatedWork W2389193565 @default.
- W1501887912 hasVolume "63" @default.
- W1501887912 isParatext "false" @default.
- W1501887912 isRetracted "false" @default.