FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1502231050> ?p ?o ?g. }

• W1502231050 endingPage "153" @default.
• W1502231050 startingPage "141" @default.
• W1502231050 abstract "Abstract HIV‐infected individuals with severe immunodeficiency are at risk of opportunistic infection (OI). Tuberculosis (TB) may occur without substantial immune suppression suggesting an early and sustained adverse impact of HIV on Mycobacterium tuberculosis (MTB)‐specific cell mediated immunity (CMI). This prospective observational cohort study aimed to observe differences in OI‐specific and MTB‐specific CMI that might underlie this. Using polychromatic flow cytometry, we compared CD4+ responses to MTB, cytomegalovirus (CMV), Epstein‐Barr virus (EBV) and Candida albicans in individuals with and without HIV infection. MTB‐specific CD4+ T‐cells were more polyfunctional than virus specific (CMV/EBV) CD4+ T‐cells which predominantly secreted IFN‐gamma (IFN‐γ) only. There was a reduced frequency of IFN‐γ and IL‐2 (IL‐2)‐dual‐MTB‐specific cells in HIV‐infected individuals, which was not apparent for the other pathogens. MTB‐specific cells were less differentiated especially compared with CMV‐specific cells. CD127 expression was relatively less frequent on MTB‐specific cells in HIV co‐infection. MTB‐specific CD4+ T‐cells PD‐1 expression was infrequent in contrast to EBV‐specific CD4+ T‐cells. The variation in the inherent quality of these CD4+ T‐cell responses and impact of HIV co‐infection may contribute to the timing of co‐infectious diseases in HIV infection." @default.
• W1502231050 created "2016-06-24" @default.
• W1502231050 creator A5003397190 @default.
• W1502231050 creator A5016729448 @default.
• W1502231050 creator A5024840524 @default.
• W1502231050 creator A5048693285 @default.
• W1502231050 creator A5064281323 @default.
• W1502231050 creator A5064420382 @default.
• W1502231050 creator A5066895396 @default.
• W1502231050 creator A5070374235 @default.
• W1502231050 creator A5077353929 @default.
• W1502231050 date "2015-04-29" @default.
• W1502231050 modified "2023-10-15" @default.
• W1502231050 title "Differences in antigen‐specific CD4+ responses to opportunistic infections in HIV infection" @default.
• W1502231050 cites W1510294620 @default.
• W1502231050 cites W1601903230 @default.
• W1502231050 cites W1816675776 @default.
• W1502231050 cites W1942062259 @default.
• W1502231050 cites W1972935005 @default.
• W1502231050 cites W1972960900 @default.
• W1502231050 cites W1990213501 @default.
• W1502231050 cites W1994340919 @default.
• W1502231050 cites W2004074456 @default.
• W1502231050 cites W2027946970 @default.
• W1502231050 cites W2032589631 @default.
• W1502231050 cites W2035054077 @default.
• W1502231050 cites W2038621149 @default.
• W1502231050 cites W2050997811 @default.
• W1502231050 cites W2061676620 @default.
• W1502231050 cites W2070552972 @default.
• W1502231050 cites W2081087993 @default.
• W1502231050 cites W2089596931 @default.
• W1502231050 cites W2097586979 @default.
• W1502231050 cites W2102799596 @default.
• W1502231050 cites W2110382769 @default.
• W1502231050 cites W2110750786 @default.
• W1502231050 cites W2113847305 @default.
• W1502231050 cites W2115377212 @default.
• W1502231050 cites W2121327992 @default.
• W1502231050 cites W2127420318 @default.
• W1502231050 cites W2127576962 @default.
• W1502231050 cites W2132007861 @default.
• W1502231050 cites W2139577725 @default.
• W1502231050 cites W2150138161 @default.
• W1502231050 cites W2150645172 @default.
• W1502231050 cites W2153352327 @default.
• W1502231050 cites W2154381591 @default.
• W1502231050 cites W2163570248 @default.
• W1502231050 cites W2168349184 @default.
• W1502231050 cites W2170799536 @default.
• W1502231050 doi "https://doi.org/10.1002/iid3.50" @default.
• W1502231050 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4578516" @default.
• W1502231050 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26417433" @default.
• W1502231050 hasPublicationYear "2015" @default.
• W1502231050 type Work @default.
• W1502231050 sameAs 1502231050 @default.
• W1502231050 citedByCount "7" @default.
• W1502231050 countsByYear W15022310502016 @default.
• W1502231050 countsByYear W15022310502017 @default.
• W1502231050 countsByYear W15022310502018 @default.
• W1502231050 countsByYear W15022310502023 @default.
• W1502231050 crossrefType "journal-article" @default.
• W1502231050 hasAuthorship W1502231050A5003397190 @default.
• W1502231050 hasAuthorship W1502231050A5016729448 @default.
• W1502231050 hasAuthorship W1502231050A5024840524 @default.
• W1502231050 hasAuthorship W1502231050A5048693285 @default.
• W1502231050 hasAuthorship W1502231050A5064281323 @default.
• W1502231050 hasAuthorship W1502231050A5064420382 @default.
• W1502231050 hasAuthorship W1502231050A5066895396 @default.
• W1502231050 hasAuthorship W1502231050A5070374235 @default.
• W1502231050 hasAuthorship W1502231050A5077353929 @default.
• W1502231050 hasBestOaLocation W15022310501 @default.
• W1502231050 hasConcept C142724271 @default.
• W1502231050 hasConcept C147483822 @default.
• W1502231050 hasConcept C159047783 @default.
• W1502231050 hasConcept C203014093 @default.
• W1502231050 hasConcept C2522874641 @default.
• W1502231050 hasConcept C2776090121 @default.
• W1502231050 hasConcept C2776409557 @default.
• W1502231050 hasConcept C2777732132 @default.
• W1502231050 hasConcept C2777975735 @default.
• W1502231050 hasConcept C2779341262 @default.
• W1502231050 hasConcept C2780727368 @default.
• W1502231050 hasConcept C2780917455 @default.
• W1502231050 hasConcept C2781069245 @default.
• W1502231050 hasConcept C71924100 @default.
• W1502231050 hasConcept C86803240 @default.
• W1502231050 hasConcept C8891405 @default.
• W1502231050 hasConcept C89423630 @default.
• W1502231050 hasConceptScore W1502231050C142724271 @default.
• W1502231050 hasConceptScore W1502231050C147483822 @default.
• W1502231050 hasConceptScore W1502231050C159047783 @default.
• W1502231050 hasConceptScore W1502231050C203014093 @default.
• W1502231050 hasConceptScore W1502231050C2522874641 @default.
• W1502231050 hasConceptScore W1502231050C2776090121 @default.
• W1502231050 hasConceptScore W1502231050C2776409557 @default.
• W1502231050 hasConceptScore W1502231050C2777732132 @default.
• W1502231050 hasConceptScore W1502231050C2777975735 @default.

• next