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- W1502775360 abstract "Sublingual immunotherapy based on grass pollen allergy immunotherapy tablets is an efficacious and well-tolerated treatment for rhinoconjunctivitis, and subcutaneous house dust mite (HDM) immunotherapy is effective against allergic asthma. Three studies have investigated a new ALK tablet for HDM allergy: two studies on tolerability in adults and children, and one on efficacy and safety in adults and adolescents with asthma. Treatment was well tolerated, mainly with mild-to-moderate local reactions pertaining to the administration site, such as temporary oral pruritus. The primary efficacy endpoint was a significant reduction in inhaled corticosteroid dose compared to baseline after 1 year of daily treatment. A positive therapeutic effect on asthma was demonstrated by a reduction of more than 80 μg/day inhaled budesonide for a group receiving six developmental units daily compared to the placebo group." @default.
- W1502775360 created "2016-06-24" @default.
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- W1502775360 date "2011-06-13" @default.
- W1502775360 modified "2023-09-26" @default.
- W1502775360 title "Tolerability and efficacy of house dust mite AIT" @default.
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- W1502775360 doi "https://doi.org/10.1111/j.1398-9995.2011.02641.x" @default.
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